基于氧化石墨烯和不规则金纳米颗粒的吗啡传感器的研制  

The preparation of morphine sensor based on graphene oxide and irregular Au nanoparticles

作　　者：赵晓慧[1] 符雪文[1] 冯亚娟[1] 罗文超[2] 黄亮亮[1] 魏玉平[1] 杨华[1] 杨云慧[1] 

机构地区：[1]云南师范大学化学化工学院,云南昆明650092 [2]华南农业大学食品科学学院,广东广州510642

出　　处：《化学传感器》2011年第1期28-34,共7页Chemical Sensors

基　　金：国家自然科学基金(No.20865006)

摘　　要：该文按照Hummers方法制备出氧化石墨,然后在水中进行超声,剥离出氧化石墨烯。利用氧化石墨烯、不规则的金纳米颗粒和壳聚糖修饰玻碳电极制成电化学传感器,并将其用于海洛因代谢物吗啡的直接电化学测定。考察了pH、工作电位等条件对传感器测定吗啡的影响。结果表明在电位为0.70V条件下该传感器检测吗啡的线性范围为1.0×10-6～3.5×10-3mol/L,检测下限为3.0×10-7mol/L。该传感器具有稳定性好,制作简单,使用寿命长等特点,为实际样品中吗啡的测定提供了一种新的简便手段。This thesis synthesized graphite oxide according to Hummers method. Then, graphene oxide was stripped by ultrasonic wave. An electrochemical sensor was prepared for the determination of morphine using graphene oxide, irregular gold and ehitosan to modify glassy carbon electrode. Experiment conditions such as pH and applied potential have been optimized. The results show that the electrode can direct response to morphine at potential of 0.70 V vs SCE with wide linear range of 1.0 × 10^-6 to 3.5× 10^-3 mol/L and the detection limit of 3.0 × 10^-7 mol/L. The sensor has good stability, simple production procedure and long lifetime. This sensor provides a new and simple means for the determination of morphine in real samples.

关 键 词：氧化石墨烯 吗啡 不规则的金纳米颗粒 传感器 

分 类 号：TB383.1[一般工业技术—材料科学与工程] TP212.2[自动化与计算机技术—检测技术与自动化装置]