基于手性Salen-Co(Ⅲ)配合物为载体的PVC电位传感器用于手性扁桃酸的识别  

Enantioselective sensing of mandelic acid by PVC potentiometric sensor based on a chiral Salen-Co(Ⅲ) complex

作　　者：李冰心[1] 侯静亚[1] 杨园园[1] 陈少珠[1] 徐岚[1] 

机构地区：[1]发光与实时分析教育部重点实验室西南大学化学化工学院,重庆400715

出　　处：《化学传感器》2011年第1期48-53,共6页Chemical Sensors

基　　金：重庆市自然科学基金资助项目(No.2008BB4263)

摘　　要：以3,5-二叔丁基水杨醛和(1R,2R)-环己二胺为原料,合成了手性(R,R)-N,N'-二(3,5-二叔丁基水杨醛)-1,2-环己二胺钴配合物[Salen-Co(Ⅲ)]作为PVC膜电极的载体。在优化的条件下,将载体、增塑剂和PVC按一定比例制作具有优良响应性能的PVC选择性电极(Salen-Co/PVC)。由于手性Salen-Co(Ⅲ)的空间构型决定其对手性扁桃酸(R-MA与S-MA)配位形成络合物的稳定性不同,使电极能优先响应R-MA,选择性系数为logK-2.36,线性范围为1.0×10-4～1.0×10-1mol/L,斜率为-52.1mV/dec,检测限为2.0×10-5mol/L。potR。In this study, chiral （R,R）-N,N＇-bis（3,5-di-tert-butyl salicylaldehyde） -1,2-diaminocyctohexane cobalt complex [Salen-Co（Ⅲ）] was prepared as the chiral selector of PVC membrane electrode which synthesized by 3,5- di-tert-butyl salicylaldehyde and （1R,2R）- diaminocyclohexane. Under the optimized conditions, PVC film electrode was prepared by uniformly mixing the carrier, plasticizer and PVC in a certain percentage and PVC selective electrode has excellent potential response（Salen-Co/PVC）. The spatial configuration of Salen-Co（Ⅲ） deterimines its coordinate with enantiomeric mandelic acid （R-MA and S-MA） to form complexes with different stability. So the electrode can preferentially respond to R-mandelic acid ,exhibiting near Nernstian response of-52.1 mV/dec in the concentration range from 1.0 × 10^-4 to 1.0 × 10^-1 mol/L with a detection limit of 2.0×10^-5 mol/L.Moreover, the elec pot trede can detect chiral R-mandelic acid with the enantlomenc selectwtlvlty coefficients log KR,S^pot was -2.36.

关 键 词：手性Salen—Co(Ⅲ)配合物 PVC膜选择性电极 手性扁桃酸 

分 类 号：TP212.2[自动化与计算机技术—检测技术与自动化装置]