贵金属纳米团簇的制备及在生物检测中的应用  

Preparation of Noble Metallic Nanoclusters and Its Application in Biological Detection

作　　者：杨群峰[1] 刘建云[1] 陈华萍[1] 王显祥[1] 黄乾明[1] 单志[1] 

机构地区：[1]四川农业大学生命科学与理学院,雅安625014

出　　处：《化学进展》2011年第5期880-892,共13页Progress in Chemistry

基　　金：四川省教育厅重点科研项目(No.08ZA053);四川农业大学科技创新基金项目(No.00731200)资助

摘　　要：介绍了贵金属纳米团簇(noble metallic nanoclusters,NMNCs)的研究现状及其作为一种新型荧光标记纳米材料在生物检测中的重要作用。重点总结了贵金属纳米团簇的优异性质、三种常用的制备方法(模板法、单分子层保护法和蚀刻法)及其近年来在生物传感器、生物探针、细胞标记及成像等领域的应用进展。简要评述和展望了贵金属纳米团簇的发展方向和应用前景。As a new kind of fluorescent material,noble metallic nanoclusters（NMNCs） has recently received increasing attention due to its unique characteristics,which make it good candidate for biological application especially in the field of biological detection.This review first addresses the typical characteristics of NMNCs,and then summarizes the recent developments of preparation methods of NMNCs（i.e.template method,monolayer protected method and ligand etching method） and its applications in the area of biological sensors,biological probes,cell labeling and imaging.Finally,the trends and future perspectives in this research area are outlined.

关 键 词：贵金属纳米团簇(NMNCs) 荧光 生物检测 生物探针 

分 类 号：O611.4[理学—无机化学] O614.12[理学—化学]