剂量变化对川乌配伍白芍镇痛作用的影响  

Influence of dosage Change of Sichuan Aconite Root Despensing Radix Paeoniae Alba on Analgesia Effect

作　　者：秦林[1] 彭欣[1] 张勤生 张少华[1] 李晓丽[1] 刘铠[1] 

机构地区：[1]山东中医药大学

出　　处：《山东中医药大学学报》1999年第4期225-227,共3页Journal of Shandong University of Traditional Chinese Medicine

基　　金：国家自然科学基金

摘　　要：采用三种疼痛实验模型，观察剂量变化对川乌、白芍配伍前后镇痛作用的影响。结果表明：剂量增大，川乌、白芍配伍前后的镇痛作用和镇痛增效作用也明显增强，剂量与作用有正相关效应。尤其是小剂量配伍组，减少川乌用量后镇痛效果仍强于或等于大剂量单味川乌组。Three kinds of experimental Pain patterns were adopted to observe the analgesia effect of dosage change of Sichuan aconite root despensing Radix Paeoniae Alba The results showed that the analgesia effect and the accumulating time delay effect of analgesia were strengthened as the dosage of the two herbs were increased,which the correlation between analgesia effect and dosage was positive The analgesia effect of low dosage group of compatibility of the two herbs is superior(or similar) to high dosage group of single ingredient of Sichuan aconite root

关 键 词：川乌 白芍 配伍 剂量 镇痛 

分 类 号：R285.5[医药卫生—中药学] R289.1[医药卫生—中医学]