哒螨酮水乳剂制备及其稳定性  

Research on the Preparation and Stability of Pyridaben EW

作　　者：杜春华[1] 李凌绪[1] 唐莎莎[1] 

机构地区：[1]青岛农业大学化学与药学院,山东青岛266109

出　　处：《农药》2011年第5期344-347,共4页Agrochemicals

基　　金：山东省优秀中青年科学家科研奖励基金项目(6209N7)

摘　　要：[目的]确定15%哒螨酮水乳剂(EW)最佳配方,考察不同因素对水乳剂稳定性的影响。[方法]以乳化剂种类及用量、制乳设备为影响因素,筛选15%哒螨酮水乳剂的最佳配方,并对各项性能进行测定。[结果]哒螨酮水乳剂的最佳配方:哒螨酮15%,二甲苯36%,复合乳化剂2#6%,正丁醇1%,乙二醇3%,去离子水加至100%;发现水乳剂冻融后分散相中位径变大、粒度分布变窄的现象。[结论]所制15%哒螨酮水乳剂中位径小、粒度分布窄,稳定性好。乳化剂种类及用量对水乳剂稳定性具有重要影响;乳化剂用量越大,分散相粒径越小。高剪切乳化设备宜于制备分散相粒度小的乳状液。分散相粒子中位径越小、粒径分布越窄,乳液体系的稳定性越好。The aims are to determine the optimal formulation of pyridaben 15%EW and investigate the influencesof various factors on the emulsion stability.[Methods]Taking the various kinds and dosage of emulsifiers,and emulsifierequipment as influencing factors,the optimal formulation of pyridaben 15%EW is screened and its performances aredetermined.[Results]The optimal formulation of pyridaben 15%EW is composed of pyridaben 15%,xylene 36%,complex emulsifiers 2#6%,n-butanol 1%,glycol 3%,and deionized water 39%.The phenomenon that D50（particlemedian diameter）of dispersion phase in EW become bigger and PSD（particle size distribution）get narrower after freezethawing is reported in this paper.[Conclusions]The formulation made by the mentioned above has small D50,narrowPSD and excellent stability.The kinds and dosage of emulsifiers have significant influences on EW stability,and thehigher emulsifiers dosage is,the smaller particle will be.High speed shearing emulsification equipment is suitable toproduce emulsion with small particle size.The work also proves that the smaller D50and the narrower PSD are,the betteremulsion stability will be.

关 键 词：哒螨酮 水乳剂 粒度 稳定性 冻融 

分 类 号：TQ454[化学工程—农药化工]