头孢羟氨苄对急性呼吸道感染的疗效研究  

Efficacy and safety of cefadroxil in the treatment of acute respiratory infection

作　　者：周燕斌[1] 谢灿茂[1] 吴俊景[1] 曾勉[1] 张孔[1] 

机构地区：[1]中山医科大学附属第一医院呼吸内科,510080

出　　处：《新医学》1999年第8期443-444,共2页Journal of New Medicine

摘　　要：目的 :进一步观察和评价头孢羟氨苄胶囊 (赛锋 )对急性呼吸道感染的临床有效性和安全性。方法 :选择急性呼吸道感染患者 60例 ,随机分成两组 ,分别给予头孢羟氨苄胶囊和头孢克洛口服治疗 ,从临床表现及实验室检验两方面对其疗效和安全性进行对比评价。结果 :头孢羟氨苄胶囊治疗急性呼吸道感染的临床有效率为 80 % ,痰分离致病菌的药敏率 89% ,细菌清除率为 84 % ,头孢克洛则分别为 73 % ,82 % ,74 % ,差异均无显著性 ( P>0 .0 5 )。前者不良反应的发生率 ( 6% )较后者 ( 17% )低。结论Objective: To evaluate the efficacy and safety of cefadroxil in the treatment of acute respiratory infection Methods: 60 patients with acute respiratory infection were randomly assigned into 2 groups: cefradroxil treated group and cefaclor treated group Clinical manifestations and laboratory profiles were compared Results: The effective rate, drug sensitivity rate of sputum isolated pathogen and bacteria eradication rate were 80%,89% and 84% respectively in cefadroxil group; while the counterpart indecies were 73%, 82% and 74% respectively in cefaclor group No significantly difference between the 2 groups ( P >0 05) was found But the incidence of side effect was lower in cefadroxil group (6%) than that in cefaclor group (17%) Conclusion: Cefadroxil is a safe and effective oral antibiotic for treatment of acute respiratory infection

关 键 词：头孢羟氨苄 头孢克洛 呼吸道感染 药物疗法 

分 类 号：R560.5[医药卫生—呼吸系统] R978.1[医药卫生—内科学]