早期发现甲状腺功能减退并发冠心病  

Early diagnosis of coronary heart disease as a complication in hypothyroidism patients

作　　者：林从容[1] 吴可贵[1] 

机构地区：[1]福建医科大学附属第一医院,350005

出　　处：《中国综合临床》1999年第4期313-314,共2页Clinical Medicine of China

摘　　要：目的探讨甲状腺功能减退（简称甲减）患者冠心病并发症时的一些特征，以便于临床早期发现冠心病并发症。方法用放射免疫法测定30例甲减患者血T3、T4、TSH值，并测定甲减患者和对照组的血总胆固醇（TCH）、甘油三酯（TG）、高密度脂蛋白（HDL）及肌酸磷酸激酶（CPK）和乳酸脱氨酶（LDH）。样本均数比较采用t检验，各指标之间的相关关系用线性回归分析并进行显著性检验。结果与对照组相比，甲减组TCH、TG增高；HDL则降低；甲减组CPK、LDH升高。甲减患者的血TCH与T3、T4呈负相关；HDL与T3、T4正相关。甲减并发冠心病组投无并发冠心病组TCH升高、HDL降低。结论甲减患者血TCH增高明显而HDL降低时应注意检查有无冠心病并发症。Objective To study the diagnosis of coronary heart disease as a complication in patients suffering from hy- pothyroidism. Methods T3,T4,TSH,TCH,TG,HDL,CPK and LDH were measured in 30 cases of hypothyroidism in order to find out some features of the hypothyroidism with complication of coronary heart disease (CHD). Results TCH,TG,CPK and LDH were increased while HDL was decreased in hypothyroidism patients. There was a negative correlation between TCH and T3, T4 and a positive correlation between HDL and T3,T4,TCH washigher while HDL was lower in patients with complication of CHD than those without this complication. Conclusion It is suggested that much attention should be paid to detect CHD complication in hypothyroidism patients with obviously increased TCH but decreased HDL.

关 键 词：甲状腺功能减退 冠心病 血脂 并发症 

分 类 号：R581.206[医药卫生—内分泌] R541.4[医药卫生—内科学]