抗菌剂改性纤维素物料及其抗菌性能(Ⅰ)——抗菌剂吸附研究实验(英文)  

MODIFICATION OF CELLULOSE MATERIALS BY ANTISEPTICS AND THEIR ANTIMICROBIAL PROPERTIES (Ⅰ)——Adsorption of Antiseptics on Cellulose Materials

作　　者：柯捷里尼科娃NE 帕纳林EF 库吉娜NP 沃芭谢娃AS 拉符连契也夫VV 侯永发[2] 李淑秀[2] 扎伊金娜NA 

机构地区：[1]俄罗斯科学院高分子化合物研究所,圣彼得堡市199004 [2]中国林业科学研究院林产化学工业研究所,江苏南京210042 [3]国立圣彼得堡药科大学,圣彼得堡市197198

出　　处：《林产化学与工业》1999年第3期53-59,共7页Chemistry and Industry of Forest Products

基　　金：国家自然科学基金委员会资助国际合作项目!( 3981112 132 9)

摘　　要：对纤维素物料与表面活性抗菌剂的吸附性能进行了研究。抗菌剂系乙烯基吡咯烷酮与巴豆酸共聚物和二甲基苄基烷基氯化物的合成聚合物 (具有广谱抗菌效果 )及其较低分子量的类聚物 (二甲基苄基烷基氯化物 )。确定纤维素物料对活性抗菌剂具有可逆吸附作用 。Adsorption properties of dressing cellulose materials with respect to surfactant antiseptics were studied.These antiseptics are a complex of the copolymer of N vinylpyrrolidone and crotonic acid with dimethylbenzylalkylammonium chloride(a synthetic polymer with a wide spectrum of antimicrobial effect)and its low molecular weight analogue(dimethylbenzylalkylammonium chloride).It was established that cellulose materials reversibly adsorb the mentioned surfactant antiseptics depending on their concentration in the initial solutions.Maximum release of surfactant antiseptics is achieved in solutions at pH=7.0.Microbiological tests of cellulose materials modified by antiseptics have shown that they exhibit antimicrobial activity.These results can be used in medical practice in clinics for imparting antimicrobial properties to dressing materials.

关 键 词：抗菌剂 纤维素 改性 吸附 抗菌性能 表面活性剂 

分 类 号：TQ352.1[化学工程] R978.7[医药卫生—药品]