子痫前期患者胎盘血流异常的高危因素及围产儿预后  

Analysis of risk factors in preeclampsia with abnormal placental blood flow and the impact on perinatal outcome

作　　者：靳瑾[1] 夏珣[1] 余艳红[1] 

机构地区：[1]南方医科大学南方医院妇产科,广州510515

出　　处：《中国临床解剖学杂志》2011年第2期229-231,共3页Chinese Journal of Clinical Anatomy

摘　　要：目的探求子痫前期患者胎盘血流异常的高危因素及其对围产儿预后的影响。方法回顾性分析255例子痫前期患者的临床资料,其中脐血流S/D比值≥3.0者82例,脐血流S/D比值<3.0者173例。B超检测脐动脉S/D比值,联合患者血压、血液流变学指标及围产儿预后进行相关性分析。结果子痫前期患者脐血流异常组母体血压及血液流变学指标较脐血流正常者有显著升高,母体血压、血液红细胞压积及D二聚体与脐血流S/D比值具有显著正相关性。子痫前期组胎儿宫内生长受限发生率及新生儿窒息率较正常对照组均有显著升高,子痫前期脐血流异常组较脐血流正常组胎儿宫内生长受限发生率及新生儿窒息率亦有显著升高。结论子痫前期患者血压增高及血液高凝是胎儿脐血流异常的高危因素,胎儿脐血流异常者易出现围产儿预后不良,对于多种高危因素并存时应积极治疗必要时终止妊娠。Objective To explore the risk factors in preeclampsia with abnormal placental blood flow and the impact on perinatal outcome.Methods Retrospective analysis of 255 patients with preeclampsia received obstetric examination in our hospital was performed.For 82 cases,the S/D value of umbilical blood flow ≥3.0,and for another 173 cases,S/D value 3.0.By comparison of blood pressure,hemorheology,S/D ratio and perinatal outcome,we made a correlation analysis.Results Maternal blood pressure and hemorheology were significantly increased in those with abnormal umbilical blood flow.Maternal blood pressure,blood hematocrit and D dimer were significantly positive correlated with umbilical S/D ratio.The incidence of intrauterine growth restriction and neonatal asphyxia was significantly higher in preeclampsia group than that of control group,as well the incidence of intrauterine growth restriction and neonatal asphyxia was significantly higher in umbilical blood flow abnormal group than that of normal group.Conclusions The risk factors of abnormal umbilical blood flow involve in the higher maternal blood pressure and the hypercoagulability.The coexistence of these factors usually prompts the fetus poor prognosis and aggressive treatment should be necessary to terminate pregnancy.

关 键 词：子痫前期 胎盘血流 高凝 危险因素 围产儿预后 

分 类 号：R683.3[医药卫生—骨科学]