高空低气压对佩戴软性角膜接触镜的透明度和视觉功能的影响  

Effects of High Altitude Hypobaria Environment on Visual Function and Contact Lens Transparency

作　　者：王善祥[1] 强东昌[1] 臧斌[1] 陈珊[1] 顾昭[1] 刘晓鹏[1] 王桂友[1] 石立勇[1] 施维茹[1] 付丽珊[1] 陈娟[1] 刘敏[1] 侯莎[1] 肖华军[1] 

机构地区：[1]空军航空医学研究所,北京100142

出　　处：《航天医学与医学工程》2011年第2期104-107,共4页Space Medicine & Medical Engineering

基　　金：全军后勤计划(AKJ10J002)

摘　　要：目的研究高空低气压环境对角膜接触镜、佩戴者视力和角膜的影响。方法 8名(16眼)男性近视受试者,屈光度为-0.5～-4.25 D,先后佩戴1种含水量为55%和2种含水量为38%的角膜接触镜,进行3次低压舱模拟高空环境实验,每次上升速率25 m/s,升至2500 m和5300 m各停留20 min,7000m停留20 min,然后以10～40 m/s的速率下降,每下降1500 m停留5 min。在每次实验前及实验过程中的每一个高度上升(或下降)前和实验后进行视力、裂隙灯显微镜检查和主观感觉评价。结果佩戴每一种镜片在不同高度之间和在不同高度佩戴3种镜片之间视力变化差异无统计学意义(P>0.05)。角膜接触镜透明度和角膜透明度无明显变化,未发现有镜下气泡形成,主观感觉视物清晰度、戴镜舒适性无明显变化,无光晕、虹视现象。结论在轻中度高空低气压环境中,佩戴软性角膜接触镜是安全的和可以耐受的。Objective To study the effect of high-altitude hypobaria environment on the contact lenses being worn,vision and cornea of wearers.Methods Eight male myopia volunteers（16 eyes）,aged from 28 to 46 years,with refraction from-0.5 to-4.25 D,took part in the experiment.Before test,they should wear the contact lens for 1 week.There were 3 types of contact lenses： ＂ocufilcon＂,with water content of 55%;＂polymacon＂（molded casting）,with water content of 38%;＂polymacon＂（centrifugal spin manufacturing process）,with water content of 38%.Each volunteer should wear the 3 types of contact lenses.The climbing rate of hypobaric chamber was 25 m/s.It stayed at 2500 m for 5 min,5300 m and 7000 m for 20 min.The descent rate was 10～40 m/s,every 1500 m stayed for 5 min.Before,during（every ascending and descending） and after every hypobaric test,visual acuity and slit lamp microscope examination were carried out.After hypobaric chamber test,injuries of cornea were checked with fluorescent staining.Results There was no significant change in visual acuity among different altitudes and contact lenses（P0.05）.During the test,transparency of contact lens and cornea had no significant change.Bubbles,Halo,Color Halo phenomena or injuries were not found.All subjects had no apparent discomfort when using contact lens.Conclusion Soft contact lens is safe and can be acceptable in different high altitude environments.

关 键 词：视觉 角膜接触镜 透明度 高空环境 低气压 

分 类 号：R852.12[医药卫生—航空、航天与航海医学]