Antibacterial Activity of Silicate Bioceramics  

作　　者：扈盛 常江 

机构地区：[1]Department of Physical Education,Huazhong Normal University [2]Biomaterials and Tissue Engineering Research Center,Shanghai Institute of Ceramics

出　　处：《Journal of Wuhan University of Technology(Materials Science)》2011年第2期227-231,共5页武汉理工大学学报（材料科学英文版）

基　　金：Funded by the Natural Science Foundation of Hubei Province(No.2009CHB006);the China Postdoctoal Science Foundation(No.20060400679);Funds of the Chinese Academy of Key Topics in Innovation Engineering(No.KGCX2-YW-207)

摘　　要：Four kinds of pure silicate ceramic particles,CaSiO3,Ca3SiO5,bredigite and akermanite were prepared and their bactericidal effects were systematically investigated.The phase compositions of these silicate ceramics were characterized by XRD.The ionic concentration measurement revealed that the Calcium （Ca） ion concentration were relatively higher in Ca3SiO5 and bredigite,and much lower in CaSiO3 and akermanite.Accordingly,the pH values of the four silicate ceramics extracts showed a positive correlation with the particle concentrations.Meanwhile,by decreasing the particle size,higher Ca ion concentrations can be achieved,leading to the increase of aqueous pH value as well.In summary,all of the four silicate ceramics tested in our study showed antibacterial effect in a dose-dependent manner.Generally,the order of their antibacterial activity against E.coli from strong to weak is Ca3SiO5,bredigite,CaSiO3 and akermanite.Four kinds of pure silicate ceramic particles,CaSiO3,Ca3SiO5,bredigite and akermanite were prepared and their bactericidal effects were systematically investigated.The phase compositions of these silicate ceramics were characterized by XRD.The ionic concentration measurement revealed that the Calcium （Ca） ion concentration were relatively higher in Ca3SiO5 and bredigite,and much lower in CaSiO3 and akermanite.Accordingly,the pH values of the four silicate ceramics extracts showed a positive correlation with the particle concentrations.Meanwhile,by decreasing the particle size,higher Ca ion concentrations can be achieved,leading to the increase of aqueous pH value as well.In summary,all of the four silicate ceramics tested in our study showed antibacterial effect in a dose-dependent manner.Generally,the order of their antibacterial activity against E.coli from strong to weak is Ca3SiO5,bredigite,CaSiO3 and akermanite.

关 键 词：silicate ceramics antibacterial activity specific surface area aqueous pH ionic concentration 

分 类 号：TQ174.75[化学工程—陶瓷工业]