光叶海桐根的化学成分(英文)  

Chemical Constituents of Pittosporum glabratum

作　　者：聂田田[1] 赵焕新[1] 白虹[1] 

机构地区：[1]山东省医学科学院药物研究所山东省罕少见病重点实验室,济南250062

出　　处：《中国天然药物》2011年第3期180-184,共5页

摘　　要：目的:对光叶海桐根的化学成分进行研究。方法:通过多种柱层析方法和制备高效液相对化合物进行分离纯化, 通过理化常数及波谱数据对其结构进行解析。结果:从光叶海桐根中分离得到 7 个化合物, 分别鉴定是 6α-羟基-京尼平苷(1), 10-O-咖啡酰基-脱乙酰基-交让木苷(2), (+)-南烛木树脂酚-3α-O-β-D-葡萄糖苷(3), (+)-南烛木树脂酚-3α-O-(6″-3,5-二甲氧基-4-羟基-苯甲酰基)-β-D-葡萄糖苷(4), (+)-南烛木树脂酚-3α-O-(6″-3-甲氧基-4-羟基-苯甲酰基)-β-D-葡萄糖苷(5), (-)-4-epi-南烛木树脂酚- 3α-O-β-D-葡萄糖苷(6)和(+)-丁香脂素-4,4'-O-双-β-D-葡萄糖苷(7)。结论:化合物 1-6 为该属首次分离, 化合物 7 为该种首次分离。AIM： To investigate the chemical constituents of Pittosporum glabratum Lindl.. METHODS： The compounds were isolated and purified by repeated column chromatography and preparative HPLC. The structures were elucidated on the basis of spectroscopic analyses and physical evidence. RESULTS： Seven compounds were isolated and identified as 6α-hydroxygeniposide （1）, 10-O-caffeoyl deacetyl daphylloside （2）, （＋）-Iyoniresinol-3α-O-β-D-glucopyranoside （3）, （＋）-lyoniresinol-3α-O-（6＂-3,5-dimethoxy- 4-hydroxybenzoyl）-β-D-glucopyranoside （4）, feruandoside [（＋）-lyoniresinol-3α-O-（6＂-3-methoxy-4-hydroxybenzoyl）-β-D-glucopyranoside] （5）, （-）-4-epi-lyoniresinol-3α-O-β-D-glucopyranoside （6） and liriodendrin [（＋）-syringaresinol-4,4＇-bis-O-β-D-glucopyranoside] （7）. CONCLUSION：Compounds 1-6 were found in the genus Pittosporum for the first time and 7 was isolated from the plant Pittosporum glabratum for the first time.

关 键 词：光叶海桐根 化学成分 环烯醚萜苷 木脂素苷 

分 类 号：R284.1[医药卫生—中药学]