胆囊结石患者手术前后血清SOD、LPO的变化  

The Changes of Serum SOD and LPO Levels in the Patients with Cholecystolithiasis before and after Operation

作　　者：邵文萍[1] 陈丽华[1] 辜庆哲[1] 

机构地区：[1]昆明医学院第一附属医院

出　　处：《广东微量元素科学》1999年第7期12-13,共2页Trace Elements Science

摘　　要：为研究胆囊结石患者血清中超氧化物岐化酶（ＳＯＤ）活性水平、过氧化脂质（ＬＰＯ）含量及其变化规律，应用黄嘌呤氧化酶法和硫代巴比妥酸法测定了４８例胆囊结石患者手术前后血清中ＳＯＤ活性和ＬＰＯ含量。结果表明，胆囊结石患者血清中ＳＯＤ的活性水平明显低于正常对照组，且术后ＳＯＤ活性水平明显提高；ＬＰＯ的含量也高于对照组，术前、术后相比，差异显著。可认为检测胆囊结石患者血清中ＳＯＤ的活性和ＬＰＯ的含量，有助于了解自由基与胆囊结石的关系。To study the changes between SOD activity and LPO content in serum of the patients with cholecystolithiasis before and after operation, the methods of xanthine oxidase and thiobarbituric acid were applied to this study. The results show that SOD activity in serum is lower than that in the control group obviously (P<001),while LPO content is higher than that in the control group significantly (P<001)The method can be used to comprehend the relation between free radical and cholecystolithiasis by determining the SOD activity and LPO content of serum in the patients with cholecystolithiasis.

关 键 词：胆囊结石 血清 术后 SOD LPO 

分 类 号：R657.420.5[医药卫生—外科学]