充血性心力衰竭患者血清及红细胞锌、铜、铁、硒含量的测定  

Determination of Zinc,Copper,Iron, Selenium in Serum and Erythrocyte of Patients with Congestive Heart Failure

作　　者：柴艳芬[1,2] 寿松涛[1,2] 姜璞 刘洪斌[1,2] 崔书章[1,2] 

机构地区：[1]天津医科大学总医院急救中心 [2]秦皇岛广播电视大学保健医院

出　　处：《广东微量元素科学》1999年第7期14-17,共4页Trace Elements Science

摘　　要：通过测定充血性心力衰竭（ＣＨＦ）患者血清和红细胞内４种微量元素（ＴＥ），了解ＴＥ与ＣＨＦ的关系。对５８例ＣＨＦ病人及４０例健康对照者采用火焰原子吸收分光光度法测定了血清和红细胞中的锌（Ｚｎ）、铜（Ｃｕ）、铁（Ｆｅ），用示波极谱法测定了硒（Ｓｅ）。结果表明，ＣＨＦ组血清Ｚｎ、Ｆｅ、Ｓｅ明显低于对照组（Ｐ＜００５～００１），血清铜升高（Ｐ＜００５）；红细胞内Ｚｎ、Ｃｕ、Ｓｅ亦明显低于对照组（Ｐ＜００５～００１），而红细胞内Ｆｅ升高（Ｐ＜００５）。提示ＣＨＦ患者体内存在Ｚｎ、Ｃｕ、Ｓｅ元素缺乏，ＣＨＦ的发展过程可能与上述元素改变有关。To evaluate the relationship between congestive heart failure(CHF)and the concentration of trace elements (TE),the levels of Zn,Cu,Fe in,serum and erythrocyte were determined by atomic absorption spectrophotometry and the level of Se was determined by polarography in 58 patients with CHF and 40 controls. The results showed that the level of serum Zn,Cu,Fe were obviously lower than those in the controls(P<005001).The level of serum Cu was much higher than that in the controls(P<005).The level of erythrocyte Zn,Cu,Se were much lower than those in the controls(P<005001),but the level of erythrocyte Fe was higher(P<005).It indicated that the development of CHF may be closely related to the changes of TE.

关 键 词：充血性心力衰竭 血清 红细胞 锌 铜 铁 硒 测定 

分 类 号：R541.61[医药卫生—心血管疾病]