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作 者:刘保新[1] 王力平[1] 徐敏[1] 黄承军[1] 唐福宇[1] 娄宇明[1] 梁柱[1] 王继[1] 梁冬波[1] 唐汉武[1]
出 处:《中国针灸》2011年第4期315-319,共5页Chinese Acupuncture & Moxibustion
基 金:广西卫生厅立项科研项目:Z2008425;广西柳州市科技局科技攻关项目:2009021518
摘 要:目的:寻找肝肾不足型绝经后骨质疏松症的较佳治疗方法。方法:将105例患者随机分为观察组、对照组A和对照组B,每组35例。对照组A口服碳酸钙D3咀嚼片,对照组B口服碳酸钙D3咀嚼片和仙灵骨葆胶囊,观察组采用口服碳酸钙D3咀嚼片配合穴位埋线治疗,急性期穴取肾俞、肝俞、夹脊、委中等,缓解期取肾俞、肝俞等,半月1次,均治疗6个月。比较各组患者疼痛视觉模拟评分(Visual Analogue Scale,VAS)、骨密度、血清雌二醇(E2)的变化和临床疗效。结果:治疗3、6个月后各组VAS疼痛积分均较治疗前明显下降(均P<0.01),观察组、对照组B较对照组A的VAS疼痛积分下降明显(均P<0.001),观察组较对照组B下降更显著(均P<0.001)。治疗6个月后,观察组与对照组B的腰椎骨密度、血清E2含量与治疗前有显著提高(均P<0.01);治疗后组间比较,观察组与对照组B骨密度均优于对照组A(P<0.01,P<0.05),观察组血清E2水平高于对照组B、对照组A(均P<0.001),对照组B优于对照组A(P<0.001)。观察组总有效率91.4%(32/35)优于对照组A(57.1%,20/35),对照组B(82.9%,29/35)亦优于对照组A。结论:穴位埋线配合口服碳酸钙D3咀嚼片可减轻肝肾不足型绝经后骨质疏松症患者疼痛程度,提高患者的骨密度与血清E2水平,是一种较优方法。Objective To explore the better treatment of postmenopausal osteoporosls of liver and kidney deficiency type. Methods One hundred and five cases were randomly divided into an observation group, a control group A and a control group B equally. In control group A, Calcichew Da tablets were taken with oral administration; in control group B, Calcichew IDa tablets and Xianling Gubao capsule were taken with oral administration. In observation group, Calcichew IDa tablets and acupoint catgut embedding were applied: Shenshu (BL 23), Ganshu (BL 18), Jiaji (EX-B 2) and Weizhong (BL 40) etc. were selected at acute stage; Shenshu (BL 23) and Ganshu (BL18 ) etc. were selected at remission stage, once every half a month and 6 months treatment in all. The Visual Analogue Scale(VAS), bone mineral density(BMD), estradiol (E2) and clinical effects were compared among groups. Results After 3 and 6 months treatment, the scores of VAS were reduced among groups (all P〈0.01) ; the reduction in observation group and eontrol group B was superior to that in control group A (all P〈0. 001), and it was more obvious in observation group than that in control group B (both P〈0. 001). After 6 months treatment, lumbar BMD and the serum level of E2 improved obviously in observation group and control group B (all P(0. 01). The comparison among groups after treatment showed that the BMD in observation group and control group B was superior to that in control group A (P〈0.01 ,P〈0.05) : the serum level of E2 in observation group was superior to that in control group B and control group A (both P〈0. 001). and it m control group B was superior to that in control group a. The total effective rate was 91.4% (32 / 35) in observation group, superior to that in control group A (57. 1%, 20/35) ; and the total effective rate was 82. 9% (29 35) in control group B, superior to that in control group A. Conclusion Calcichew D3 tablets and acupoint catgut embedding therapy c
分 类 号:R246.3[医药卫生—针灸推拿学]
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