扩张型心肌病与缺血性心肌病中C-反应蛋白的定量分析  

Quantitative analysis of serum C-reactive protein in the patients with ischemic cardiomyopathy and dilated cardiomyopathy

作　　者：宋艳秋[1] 张辉[1] 

机构地区：[1]郑州大学第四附属医院心内科,河南郑州450044

出　　处：《海南医学院学报》2011年第3期323-324,327,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020110064)~~

摘　　要：目的:探讨C-反应蛋白(CRP)在扩张型心肌病与缺血型心肌病患者中的定量变化。方法:59例心肌病患者通过冠脉造影检查后分为扩张型心肌病组(DCM组),28例和缺血型心肌病组(ICM组)31例。测定患者在不同的NYHA分级时血清CRP浓度。结果:ICM组患者血清CRP平均浓度明显高于DCM组(P<0.01)。在相同NYHA时,ICM组患者的血清CRP浓度明显高于DCM组(P<0.01)。两组患者血清CRP浓度均随心衰程度加重而增高,NYHAⅢ和Ⅳ级患者血清CRP浓度明显高于NYHAⅠ和Ⅱ级(P<0.01)。结论:CRP是鉴别扩张型心肌病与缺血性心肌病的一个重要指标。Objective：To investigate the level of serum C-reactive protein（CRP） in the patients with ischemic cardiomyopathy（ICM） and dilated cardiomyopathy（DCM）.Methods：According to the results of coronary angiography,cardiomyopathy patients were divided into Group DCM（28 cases） showing normal coronary arteries and Group ICM（31 cases）.CRP levels were measured at different NYHA cardiac function grade.Results：CRP levels in patients with ICM were significantly higher than those in patients with DCM（P0.01）.At the same class of cardiac function,CRP levels in patients with ICM were significantly higher than those in patients with DCM.Both in ICM group and DCM group,higher the grade of cardiac function,higher the levels of serum CRP.Patients at NYHA Ⅲ and Ⅳ had higher CRP levels compared with patients at NYHAⅠand NYHAⅡin both groups（P0.01）.Conclusions：The level of CRP is important index for differentiate ICM from DCM.

关 键 词：心肌病 扩张型 缺血性 C-反应蛋白 

分 类 号：R542.2[医药卫生—心血管疾病] R541.6[医药卫生—内科学]