雏鸡感染IBV后气管、肺及肾组织中血管活性肠肽(VIP)动态变化  

Changes of VIP in trachea,lung and kidney tissue of chickens infected with avian infectious bronchitis virus

作　　者：彭芳珍[1] 佘锐萍[2] 胡艳欣[2] 靳红[3] 

机构地区：[1]安徽安庆师范学院生命科学学院,安徽安庆246011 [2]中国农业大学动物医学院,北京100193 [3]农业部,北京100026

出　　处：《中国兽医学报》2011年第5期645-648,共4页Chinese Journal of Veterinary Science

基　　金：国家自然科学基金资助项目(30471301);国家科技支撑计划子课题资助项目(2008BADB4B07-10);2011年安徽高校省级自然科学研究资助项目(KJ2011Z238)

摘　　要：80只14日龄SPF鸡随机均分为试验组和对照组,试验组用鸡传染性支气管炎病毒M41株人工感染,于感染后1,3,5,7,11,15 d分别测定试验组及对照组气管、肺和肾组织中血管活性肠肽(VIP)含量,探讨脑肠肽类物质VIP在鸡传染性支气管炎发病过程中的作用。结果表明:试验组气管组织中VIP含量自感染后一直高于对照组,并且于7,11 d VIP含量显著高于对照组(P<0.05);肺组织中VIP含量未出现明显变化;肾组织中VIP含量自感染后7 d开始上升,并且于7,11 d显著高于对照组(P<0.05)。提示脑肠肽类物质VIP可能参与调节了呼吸系统疾病鸡传染性支气管炎的发生发展过程。Eighty 14-day-old chickens were randomly divided into two groups.40 chickens were used for infection and 40 chickens were served as control.Vasoactive intestinal peptide（VIP） of trachea,lung and kidney tissue were measured at day 1,3,5,7,11,15 post infection（PI）,respectively.The results indicated that the content of VIP in trachea tissue in experiment group started to increase at day 1 PI and significantly higher than that of control group at day 7,11 PI.But the VIP in lung tissue was no significant changes during the experiment.The content of VIP in kidney tissue of experiment group started to increase at day 7 PI and significantly higher than that of control group at day 7,11 PI.The results implied that VIP may regulate the occurrence and development of avian infectious bronchitis.

关 键 词：IBV 气管 肺 肾 VIP 

分 类 号：S852.65[农业科学—基础兽医学]