Z-N催化剂内给电子体——2,2-二苯基-1,3-丙二醇二甲醚的合成研究  

Synthesis of the internal electron donor in Z-N catalyst—2,2-diphenyl-1,3-dimethoxypropane

作　　者：刘敏[1] 孙文姣[1] 李效军[1] 雒佳莉[1] 许文倩[1] 闫林林[1] 

机构地区：[1]河北工业大学化工学院,天津300130

出　　处：《化学试剂》2011年第5期420-422,447,共4页Chemical Reagents

摘　　要：以二苯甲酮、氯乙酸乙酯、甲醛水溶液和碘甲烷为主要原料,经达森缩合、酯水解、脱羧、重排、缩合歧化和醚化反应合成了标题化合物,并对合成反应中的关键影响因素进行了研究。在适宜的反应条件下,目标产物的总收率61.3%(以二苯甲酮计),产品气相色谱纯度为97.4%。1HNMR分析确定了目标化合物的结构。2,2-Diphenyl-1,3-dimethoxypropane was synthesized from benzophenone,ethyl chloroacetate,aqueous formaldehyde and iodomethane by the Darzens condensation,ester hydrolysis,decarboxylation,rearrangement,condensation/disproportionantion and etherification and the main factors effecting the reactions were studied.Upon the optimized synthetic conditions the overall yield of the product was 61.3%,with a purity of 97.4%（analyzed by GC）.The structures of the products were elucidated by 1HNMR.

关 键 词：2 2-二苯基-1 3-丙二醇二甲醚 2 2-二苯基-1 3-丙二醇 二苯乙醛 二苯甲酮 

分 类 号：O622.4[理学—有机化学]