红厚壳属植物中色满酮衍生物的研究进展  

Research progress of chromanone derivatives from Calophyllum

作　　者：王欢[1,2] 王跃虎[2] 李娟[1] 陈丽娟[1] 

机构地区：[1]云南农业大学农学与生物技术学院,云南昆明650201 [2]中国科学院昆明植物研究所,云南昆明650204

出　　处：《中国中药杂志》2011年第9期1115-1121,共7页China Journal of Chinese Materia Medica

摘　　要：红厚壳属植物具有很高的药用价值,常作为民间药物用于治疗疾病,如牙痛、风湿、腹泻、慢性胃溃疡、皮肤感染以及创伤。该属植物富含色满酮衍生物,且此类次生代谢产物具有抗病毒、抗真菌、抗细菌以及细胞毒等药理活性。为了对红厚壳属植物中的色满酮衍生物有更完整的了解,以便从我国红厚壳属植物中寻找新的活性成分,故对该属植物中色满酮衍生物的化学结构和药理活性进行了概述,并探讨了此类成分可能的生源途径。Calophyllum plants have great pharmaceutical value.Some species of this genus are used in folk medicine to treat and cure diseases,such as toothache,rheumatism,diarrhea,chronic ulcers,skin infections,and wounds.The genus is known to be rich in chromanone derivatives,and some of these compounds have antiviral,antifungal,antibacterial,cytotoxic,and other activities.In order to come to a more complete understanding of chromanone derivatives and gain new bioactive constituents from Calophyllum,chemical structures,pharmacological activities,and biogenesis of chromanone derivatives from Calophyllum have been discussed in this review.

关 键 词：藤黄科 红厚壳属 色满酮衍生物 

分 类 号：R284.1[医药卫生—中药学]