矿物药青礞石、煅青礞石无机元素的ICP-MS分析  

ICP-MS Analysis of Inorganic Elements of Mineral Medicine Chloriti lapis and Processed One

作　　者：刘圣金[1] 吴德康[1] 林瑞超[2] 刘训红[1] 胡秋萍[1] 孔庆友[3] 

机构地区：[1]南京中医药大学,南京市210046 [2]中国药品生物制品检定所,北京市100050 [3]南京大学,南京市210093

出　　处：《中国药房》2011年第19期1777-1780,共4页China Pharmacy

基　　金："十一五"国家科技支撑计划项目子课题(2006BAI55B02-13);江苏省普通高校研究生科研创新计划项目(CX09B-282Z);江苏省老中医药专家师承项目(2009)

摘　　要：目的:测定青礞石及其煅制品中无机元素的含量。方法:采用电感耦合等离子体-质谱法分析青礞石与煅青礞石中的无机元素,用SPSS16.0统计软件对数据进行主成分和相关性分析。结果:检测了青礞石、煅青礞石中的25种元素,其中Si、Fe、Mg、Al、Ca、K、Na7种元素为两者的主要成分,累积贡献率分别达到90.700%和100.000%。Ti的平均含量也较高,分别达到6.3562mg·g-1和5.5546mg·g-1。部分元素间显示出一定的相关性。煅青礞石的无机元素含量大多较青礞石的含量低。结论:本试验结果可为青礞石药材的有效性、安全性评价及质量标准制定提供科学的参考依据。OBJECTIVE：To determine the contents of the inorganic elements in Chloriti lapis and processed one. METHODS：The inorganic elements of C. lapis and processed one were analyzed by inductively coupled plasma-mass spectrography（ICP-MS） . Main components and correlation were analyzed using SPSS16.0 software. RESULTS：25 inorganic elements were determined. Main components were Si,Fe,Mg,Al,Ca,K,Na and cumulative rate reached at 90.700% and 100.000%. Average content of Ti was relatively high and reached 6.356 2 mg·g-1 and 5.554 6 mg·g-1. And there were correlations among some inorganic elements. The content of inorganic elements in processed C. lapis was lower than that of C. Lapis. CONCLUSION：The study provides a scientific reference for effectiveness and safety evaluation and the formulation of quality standard of C. Lapis.

关 键 词：矿物药 青礞石 煅青礞石 无机元素 电感耦合等离子体-质谱法 

分 类 号：R282.76[医药卫生—中药学] R931.76[医药卫生—中医学]