苍葛止泻灵诱生鼠干扰素的实验研究  

Experimental Studies on Cang Ge Zhixieling in Inducing Interferon in Mice

作　　者：韩新民[1] 陆茵 巢建国 姚堃[2] 吴筱玲[2] 

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210029 [2]南京医科大学,210029

出　　处：《南京中医药大学学报》1999年第5期293-294,共2页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省教委资助!( 970 0 86 )

摘　　要：目的:观察苍葛止泻灵在小鼠体内诱生干扰素的作用。方法:微量细胞病变抑制法(CPE)测定干扰素效价。结果:苍葛止泻灵高、中剂量组具有明显诱生鼠干扰素的作用,与对照组比较P<0.01,其中腹腔注射组高于灌胃组。诱生时间24h达高峰,其效价为(256±24.8)U/ml。结论:苍葛止泻灵具有诱生和促诱生鼠干扰素的作用。OBJECTIVE: To observe the function of Cang ( Atractylodes Lancea )and Ge( Pueraria Lobata )Zhixieling in inducing interferon in mice.METHOD:CPE method was used to determine interferon titer.RESULT:Interferon in mice can be induced by Cang Ge Zhixieling after being taken either large or moderate in dosage by them with P <0.01 in comparison with the control group.Furthermore,abdominal cavity injection group is more capable in inducing the interferon than the stomach perfusion group.Fastigium with a titer of (256±24.8)U/ml ws reached 24 h after inducement.CONCLUSION:Cang Ge Zhixieling has the effect in inducing interferon in mice.

关 键 词：苍葛止泻灵 药理 动物实验 干扰素 中药 

分 类 号：R286.87[医药卫生—中药学]