消瘿散结膏对实验性家兔甲状腺肿的影响  

Effect of Xiao Ying San Jie Adhesive Plaster on Simulating Goiter Rabbit

作　　者：卢金福[1] 王旭 陈金锭[2] 许芝银[2] 陆茵[1] 陈旺意 

机构地区：[1]南京中医药大学中药学院,江苏南京210029 [2]江苏省中医院

出　　处：《南京中医药大学学报》1999年第5期295-296,共2页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省教委自然科学基金!( 95 0 6 3 )

摘　　要：目的:观察消瘿散结膏(简称消瘿膏)对丙基硫氧嘧啶致家兔甲状腺肿模型的影响。方法:每日给家兔灌服丙基硫氧嘧啶(100mg/kg),同时将其颈部用10%Na2S脱毛(面积约16cm2)后,涂以消瘿膏。3周后处死,以甲状腺、垂体、胸腺及脾的脏器指数和血清T3、T4含量为指标,观察药物的作用。结果:消瘿膏能明显抑制由丙基硫氧嘧啶所致的甲状腺肿大,使升高的垂体指数具有趋于正常的趋势,但未见对胸腺、脾指数及血清T3、T4含量的影响。结论:消瘿膏具有较好的抗甲状腺肿的作用,为临床应用提供了一定的依据。OBJECTIVE:To observe the effect of Xiao ying San Jie Adhesive Plaster (short for Xiao Ying Adhesive Plaster)on propylthiouracil goiter rabbit models(PTU).METHOD:PTU(100 mg/kg) was used daily for the rabbit model. Xiao Ying Adhesive Plaster was applied to the cervical part where the hair was shed by 10% Na 2s. Three weeks later the rabbit was killed for observation on the effect of the plaster with thyroid, hypophysis, thymus gland and spleen coefficient as indexes.RESULT:Xiao Ying adhesive plaster was effective in inhibiting thyroid enlargement caused hypophysis coefficient, but no influence was found on thymus gland, spleen coefficient, T 3 and T 4 content of blood serum .CONCLUSION:Xiao Ying Adhesive Plaster had good effect in anti-goiter. The study provided a basis for its clinical application .

关 键 词：消瘿散结膏 外用 甲状腺肿 中医药疗法 

分 类 号：R259.813[医药卫生—中西医结合]