心房不同部位起搏对家兔房室结电生理特性的影响  

Effect of different pacing sites in atrium on the electrophysiology of atrioventricular node in isolated rabbit heart

作　　者：杨波[1] 周纪宁[1] 黄从新[1] 江洪[1] 唐其柱[1] 王腾[1] 李庚山[1] 

机构地区：[1]湖北医科大学附属第一医院心内科,430060

出　　处：《临床心电学杂志》1999年第3期151-152,共2页Journal of Clinical Electrocardiology

基　　金：湖北省教委资助

摘　　要：目的　探讨心房不同部位起搏对离体家兔房室结（ Ａ Ｖ Ｎ）电生理特性的影响。方法　采用等量血液－ 台氏液，经 Ｌａｎｇｅｎｄｏｒｆ装置持续灌流离体兔心，分别从房间隔（ Ｉ Ａ Ｓ）和终末嵴（ Ｃ Ｔ）刺激心脏，观察从上述两个部位起搏心脏时， Ａ Ｖ Ｎ 前传的各项电生理参数。结果　从 Ｉ Ａ Ｓ和 Ｃ Ｔ 起搏时， Ａ Ｈ 间期、 Ａ Ｖ Ｎ功能不应期（ Ａ Ｖ Ｎ－ Ｆ Ｒ Ｐ）、 Ａ Ｖ Ｎ 前传文氏周期（ Ａ Ｖ Ｎ－ Ｗ Ｃ Ｌ）无显著差异。结论　心房不同部位起搏心脏对该模型兔心 Ａ Ｖ Ｎ 电生理特性无影响。Objective This paper was to investigate the effect of different pacing sites in atrium on the electrophysiology of atrioventricular node(AVN) in isolated rabbit heart.Method Isolated rabbit hearts were constantly perfused using the mixture of equal volume of blood and Tyrode's solution via Langendorf apparatus.The perfused rabbit heart was paced from crista terminals(CT)and interatrial septum (IAS) and the electrophsiological parameters of AVN were recorded and analyzed,respectively.Results It was showed that when paced from both sites,electrophsiological parameters of AVN including AH interval,functional refractory period,Weckbech cycle length differentiated nonsignificantly.Conclusion Pacing from different sites in atrium has no effect on the electrophysiology of AVN in this animal mode.

关 键 词：房室结 电生理 兔 起搏 

分 类 号：R331.38[医药卫生—人体生理学]