三苯双脒治疗钩虫感染效果  

Efficacy of tribendimdine in treatment of hookworm infection

作　　者：田利光[1] 程国金[2] 汪峰峰[3] 郭俭[1] 蔡玉春[1] 汪天平[3] 陈家旭[1] 周晓农[1] 

机构地区：[1]中国疾病预防控制中心寄生虫病预防控制所,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,卫生部寄生虫病原与媒介生物学重点实验室,上海200025 [2]安徽省阜阳市疾病预防控制中心 [3]安徽省血吸虫病防治研究所

出　　处：《中国血吸虫病防治杂志》2011年第2期202-203,共2页Chinese Journal of Schistosomiasis Control

基　　金：国家科技支撑计划(2005DKA21104、2007BAC03A02);国家重大科技专项(2008ZX10004-011)

摘　　要：目的了解三苯双脒治疗钩虫感染的效果。方法以横断面调查中发现的钩虫感染者为研究对象,随机分成实验组和对照组,分别给予三苯双脒和阿苯达唑治疗,观察两组钩虫感染转阴率及不良反应情况。结果共调查47例钩虫感染者,实验组23例,对照组24例。三苯双脒和阿苯达唑治疗钩虫感染转阴率分别为95.65%和95.83%,不良反应率分别为8.70%和8.33%,差异均无统计学意义(P均>0.05)。结论三苯双脒治疗钩虫感染的疗效与阿苯达唑相仿。Objective To study the efficacy of tribendimdine in the treatment of hookworm infection.Methods Forty-seven cases of hookworm infection detected in a cross-sectional study were selected and randomly divided into two groups,one was experimental group（23 cases） treated with tribendimdine and the other was control group（24 cases） treated with albendazole.The negative conversion rates and the incidence rates of adverse effects in the two groups were observed and compared.Results The negative conversion rates and the incidence rates of adverse effects of the two groups were 95.65% and 95.83%,8.70% and 8.33%,respectively,there were no statistical differences（both P values0.05）.Conclusion The efficacy of tribendimdine in the treatment of hookworm infection is similar to albendazole.

关 键 词：钩虫 三苯双脒 阿苯达唑 治疗效果 

分 类 号：R383.13[医药卫生—医学寄生虫学]