喹乙醇在动物血浆与组织间残留分布规律研究及相关性分析  

Analysis on the distribution and correlation of residues of Olaquindox in animal plasma and tissue

作　　者：张锦红[1] 曾昭智[1] 葛长荣[2] 

机构地区：[1]广东药学院实验动物中心,广东广州510008 [2]云南农业大学动物营养与饲料重点实验室,云南昆明650201

出　　处：《中国动物保健》2011年第5期13-15,共3页China Animal Health

基　　金：国家科技支撑计划资助项目(2006BAD14B03-6);国家科技部攻关项目资助(2003BA766C)

摘　　要：试验采用高效液相色谱分析法,对饲喂含有不同浓度喹乙醇饲料(75mg/kg、100mg/kg、125mg/kg)的猪体组织(肝脏、肾脏、肌肉)和血浆中喹乙醇含量进行检测,分析喹乙醇在猪体内的残留分布,探讨喹乙醇在血浆中的含量与猪体内组织的残留含量的相关性。结果表明:饲料中喹乙醇添加量与组织和血浆中残留量均呈线性相关关系;同一浓度的喹乙醇添加量在猪组织和血浆中的残留量分布:肝脏>肾脏>肌肉>血浆;建立的血浆与组织间残留量的回归方程具有较高的可靠性。Using high performance liquid chromatography, detected the content of Olaquindox in tissue （liver, kidney, muscle） and plasma of pig which fed with different concentrations of Olaquindox feed （75mg/kg, 100mg/kg, 125mg/kg）. Studied on the correlation of residues of Olaquindox in animal plasma and tissue and the distribution of residues in the body. Results showed that there is a linear correlation between the amount of O- laquindox in feed and the residues in plasma and tissues, The residual distribution of the same concentration Olaquindox in pig tissue and plasma is： liver〉 Kidney〉 muscle〉 plasma. There is a high reliability for estab- lishing the regression equation of the residues in plasma and tissue.

关 键 词：喹乙醇 高效液相色谱 残留分布 相关性 

分 类 号：S859.84[农业科学—临床兽医学]