应用肺灌注显像预测病人肺动脉压力  

Evaluation of Pulmonary Artery Pressure by Lung Perfusion Scintigraphy

作　　者：张永[1,2] 石美鑫[1] 毛履琰[1] 金少津[1,3] 

机构地区：[1]上海医科大学华山医院,200040 [2]首都医科大学附属北京红十字朝阳医院心外科,100020 [3]中山医院胸外科,200032

出　　处：《高血压杂志》1999年第3期221-224,共4页Chinese Journal of Hypertension

摘　　要：研究 Ｌ Ｓ法在预测病人肺动脉压力方面的功效。　方法：对２２ 例患者于术前行肺灌注显像研究，应用 Ｌ Ｓ法计算出肺动脉压力（ Ｐ Ａ Ｐ），并与病人心导管资料或术中测压资料做对比。　结果：计算出的 Ｐ Ａ Ｐ与测出的 Ｐ Ａ Ｐ呈明显相关（ｒ＝ ０．９２， Ｐ＝ ０００１），与病人心胸比率（ｒ＝ ０．７５， Ｐ＝ ０．０００１），肺细血管嵌压（ｒ＝ ０．９０， Ｐ＝ ０．０００９）和全肺阻力（ｒ＝０．８０， Ｐ＝ ０．０１）明显相关；该方法诊断肺动脉高压的敏感度和特异度均为 ９２％ ，阳性抑然比为１１．５，阴性抑然比为０．０８７。　结论： Ｌ Ｓ法可准确直接地预测病人肺动脉压力。Objective:To evaluate the value of lung perfusion scintigraphy in estimation of pulmonary artery pressure in patients with various heart diseases.\ Methods: 99 mTc MAA lung perfusion scintigraphy was performed in 22 patients with various heart diseases. Patients were in lateral decubitus position. The pulmonary artery pressure(PAP) was calculated by LS method.\ Results:The calculated PAP, when comparison with hemodynamic parameters, correlated strongly with measured PAP( r= 0.92, P= 0001),pulmonary capillary wedge pressure( r= 0.90, P= 0.0009) and total pulmonary resistance index( r= 0.80, P= 0.01),respectively. The sensitivity and specificity of LS method for diagnosis of pulmonary hypertension were 92%. \ Conclusion:LS method of lung perfusion scintigraphy could estimate pulmonary artery pressure efficiently and directly. This method deserve to be further investigation.

关 键 词：肺灌注显像 肺动脉压力 临床实验 

分 类 号：R541.5[医药卫生—心血管疾病] R814.43[医药卫生—内科学]