样本接力跟踪检测质量控制法的初步应用  

Initial Applications of Quality Controlling Method for Sample Following-Detection

作　　者：魏志武[1] 居军[2] 

机构地区：[1]甘肃省白银市第二人民医院检验科,甘肃白银730900 [2]甘肃省人民医院甘肃省临床检验中心,兰州730000

出　　处：《现代检验医学杂志》2011年第2期15-18,共4页Journal of Modern Laboratory Medicine

摘　　要：目的 建立一种以＂接力＂模式选取批次样本作为＂质控品＂,＂ 零成本＂便捷开展室内质控的方法.方法 使用BC-5500五分类血细胞仪;通过预先监测统计,选定样本能在接力间隔期间（2～4℃,1～3 d）相对稳定的项目（WBC）开展质控;在仪器校准后立即开展第1批患者样本的检测（将此批检测假定为＂0＂偏差%、＂0＂偏差）,从中选取1份最靠近校准品定值的样本作为＂集中值质控品＂,在第2批（d）检测中带入复检,并在批次中选出第2份＂集中值质控品＂,如此随日常检测批次不断延续;此编排可使＂质控品＂批次间的偏差%（表象偏差%）具备＂交接性＂,以此为依据同步计算每份＂质控品＂的＂累积差值（真相差值）＂,从而具备对＂0＂偏差的＂跟踪性＂;根据累积差值的性质将其＂移植＂于s=√Σ（x^-）^2/n-1公式,得到＂累积差值标准差公式＂：Sb=√Σ（0-Si）^2/n-1,计算Sb,确定对累积差值的控制范围;统计偏差%组绝对值数据,确定对偏差%的控制范围;最后以L-J法图形表达方式同步控制＂累积差值＂和＂偏差%＂.结果 WBC数据图形模型显示：接力法既控制＂真相差值＂又控制＂表象偏差%＂,可以如L-J法一样显示检测系统误差变化.结论 接力法能赋予普通血样以＂质控品＂属性;累积差值＂移植＂于L-J法统计公式后,使接力法兼具统计学优点;相对于质量差的商品质控品项目（WBC）,接力法更具效果和效益.Objective Building a ＂relay＂ mode selected batches of samples as a ＂quality control materials＂ and ＂zero cost＂ and convenient way to carry out internal quality control. Methods Using the BC-5500 hematology analyzer;through the pre-monitoring statistics,the relay can be selected sample interval （2-4℃, 1-3 days） the relative stability of the project （WBC） to carry out quality control. Immediately after the calibration of the instrument to carry out tbe first batch of patient samples 1 detection （detection of this grant is assumed to be ＂0＂ deviation% ,＂0＂ deviation） ,select from 1 items closest to the calibration value of the sample as a ＂focus on value QC products＂,in Batch 2（days） detection into the re-examination, and selected in the first two batches were ＂focused on the value of quality control products＂, so keep continuity with the daily batch testing. This arrangement will enable ＂quality control material＂ deviation % between batches （appearances deviation % ） l;-ve the ＂handover＂ of,as a basis for calculating each sync, ＂control materials＂ and ＂the cumulative difference （the difference between the truth）＂,which have the ＂0＂ deviation ＂traceability＂. According to the cumulative nature of the difference between its ＂transplant＂ in the formula s =√Σ（x^-）^2/n-1 to obtain ＂the cumulative difference between the standard deviation formula＂ Sb=√Σ（0-Si）^2/n-1,calculations to determine the scope of control of the cumulative difference. Absolute deviation percentage group statistical data to determine the extent of deviation% of control;Finally,a graphical representation of L-J synchronization method ＂cumulative difference＂ and ＂deviation percentage. ＂Results Graphical model data showed WBC：Relay method both control ＂the difference between the truth＂ and control ＂appearances deviation%＂,such as the L-J method can detect systematic errors is shown as a change. Conclusion Relay common law can give blood

关 键 词：以样本作为质控品 接力跟踪检测 偏差%累积差值质控法 

分 类 号：R446[医药卫生—诊断学]