肾动态显像在临床-病理分离的IgA肾病治疗中的应用  

Renal dynamic imaging in clinical-pathological separation of IgA nephrology application

作　　者：王丽雅[1] 张鹏[1] 吕学爱[1] 

机构地区：[1]泰安市中心医院,山东271000

出　　处：《社区医学杂志》2011年第8期33-34,共2页Journal Of Community Medicine

摘　　要：目的研究肾动态显像在指导治疗临床-病理分离的IgA肾病中的应用价值。方法选择经病理学证实为IgA肾病而临床表现轻微患者62例,对其肾小球、肾小管间质和血管损害程度进行LEE氏分级。全部患者均接受99mTc-DTPA肾动态显像,计算出灌注指数(PI)、肾小球滤过率(GFR)、20m in清除率(C20)分析不同病理分级之间显像指标与病理积分间的关系。结果 PI与血管损害积分正相关(P<0.01)GFR与肾小球损害(P<0.01)及肾小管间质损害积分(P<0.05)呈负相关,C20与肾小管间质损害积分(P<0.01)呈负相关。结论肾动态显像结果与肾脏组织病理学改变明显相关、能较好地反映病理损伤的进程,对指导治疗临床-病理分离的IgA肾病有重要价值。Objective To research in the treatment of renal dynamic imaging guide clinical application of separation of IgA nephropathy value.Methods Sixty-two patients with IgAN were divided into four groups according to Lee＇s histological classification.All patients underwent renal dynamic imaging with 99mTc-DTPA.The relationship between pathological and imaging parameters among all Lee＇s groups were analyzed.Results The results indicated that there was a positive correlation between PI and the vessel lesion score（P0.01）,negative correlation between GFR and the glomerular lesion score（P0.01） and tubulo-interstitial lesion score（P0.05）,and negative correlation between C20 and tubulointerstitial lesion score（P0.01）.Conclusions The results of renal dynamic imaging closely relate to the renal pathological changes of IgAN,and can better reflect the degree of pathological lesions.To guide for clinical pathologic separation of IgAN are of great value.

关 键 词：肾小球肾炎 IGA 放射性核素显像 

分 类 号：R692.31[医药卫生—泌尿科学] R817.4[医药卫生—外科学]