盐藻素抗氧化及对血清内皮素和肿瘤坏死因子的影响  

Dunaliella Salina Anti- oxidative Effect and Impact on Endothelin and Tumor Necrosis Factor

作　　者：刘维佳[1] 崔坤敏[1] 夏立营[1] 李明喜[1] 周佩云[1] 葛文津[1] 

机构地区：[1]中国中医科学院西苑医院,北京100091

出　　处：《中国现代医生》2011年第13期3-4,6,共3页China Modern Doctor

摘　　要：目的研究盐藻素对亚健康人群抗氧化作用和对血清内皮素、C-反应蛋白、肿瘤坏死因子的影响。方法共收集亚健康患者72例,分为2组,一组给予盐藻素(35例),另一组给予番茄红素(37例),测定两组患者的抗氧化指标、血清内皮素、C-反应蛋白、肿瘤坏死因子等,分析上述指标前后变化。结果盐藻素组血清C-反应蛋白降低、肿瘤坏死因子升高,与对照组差异无统计学意义;MDA降低程度、GSH-Px升高程度,与对照组比较差异具统计学意义。结论盐藻素可降低C-反应蛋白、升高肿瘤坏死因子、有明显的抗氧化作用。Objective To observe the anti-oxidative effect,the change of endothelin,C-reactive protein and tumor necrosis factor of dunaliella salina on sub-health population. Methods The 72 sub-heahh patients were divided into two groups,which one group（n=35） was treated by dunaliella salina and another group （n=37）was treated by lycopene. Antioxidant index,endothelin, C-reactive protein and tumor necrosis factor of the two groups were compared and analyzed. Results There was no significant difference in the change of C-reactive protein and tumor necrosis factor between two groups. The decrease of MDA and the increase of GSH-Px in the group of dunaliella salina were significantly higher than the group of lycopene. Conclusion Dunaliella salina could decrease C-reactive protein and increase tumor necrosis factor. So it had a significant anti-oxidative effect.

关 键 词：人体试验 盐藻素 抗氧化 血清内皮素 C-反应蛋白 肿瘤坏死因子 

分 类 号：R34[医药卫生—基础医学]