慢性充血性心力衰竭血甲状腺激素变化的探讨  

INVESTICATION OF CHANGES OF BLOOD THYROXIN IN PATIENTS WITH CHRONIC CONGESTIVE HEART FAILURE

作　　者：陶月玉[1] 陈宝仁[2] 柯永胜[1] 张桂发[1] 李苏[1] 王荣鑫[3] 吴采月[3] 

机构地区：[1]皖南医学院附属弋矶山医院内科 [2]皖南医学院 [3]皖南医学院附属弋矶山医院同位素室

出　　处：《皖南医学院学报》1990年第3期27-29,共3页Journal of Wannan Medical College

摘　　要：放射免疫方法测定67例慢性充血性心力衰竭患者和20例正常人血清T_3、T_4和TSH含量。结果显示:CCHF组血清T_3、T_4含量显著低于正常人(P<0.001～0.05);心衰程度越重,血清T_3、T_4水平越低。治疗后的CCHF患者血清T_3、T_4水平可有不同程度的回升,但心功能Ⅳ级组T_3、T_4含量仍显著低于正常人(P<0.05)。提示:CCHF患者低T_3、T_4水平部分是可逆的,T_3、T_4水平过于减低的明显心衰患者可能预后不良。The serum T_3, T_4 and TSH concentrations of 67 patiens with chronic congestive heart failure (CCHF) and 20 normal cases were detemined with radioimmunoassay. The results showed: the serum T_3 and T_4 concentrations of the patients were much lower than those of the normal cases (P<0.001-0.05); the more severe the heart failure was, the lower the serum thyroxin level of patients; after proper treatment the serum T_3 and T_4 level in some of the pa- tients was restored to some degree, but it remained nuch lower than those of the normal subjects in patients with the fourth grade of heart function (P<0.05). It suggests that the low serum T_3 and T_4 level is partly restorable and in patients with severe heart failure the low concentrations of both T_3 and T_4 often presages a poor prognosis.

关 键 词：心力衰竭 甲状腺激素 血清 诊断 

分 类 号：R541.610.4[医药卫生—心血管疾病]