137例阴道真菌感染及耐药性分析  

Analysis of vaginal fungal infections and drug resistance in 137 cases

作　　者：谭正芳 

机构地区：[1]湖南省永州市人民医院检验科,425000

出　　处：《中国实用医药》2011年第11期29-30,共2页China Practical Medicine

摘　　要：目的了解女性阴道中真菌感染及耐药情况。方法将白带常规中涂片镜检真菌阳性患者的阴道分泌物的标本进行培养、鉴定和药敏试验。结果 137份送检标本中,白色假丝酵母菌(84株,61.3%)检出率最高,其次是光滑球拟酵母菌(19株,13.9%),热带假丝酵母菌(15株,10.9%),克柔假丝酵母菌(7株,5.1%),其他真菌(12株,8.8%)。分离菌株对氟胞嘧啶,两性霉素B和伏立康唑的敏感率均>90%,伊曲康唑敏感率为84.7%,氟康唑敏感率为70.8%。结论女性阴道真菌感染的白色假丝酵母菌为主。氟胞嘧啶,两性霉素B和伏立康唑敏感率较高,氟康唑和伊曲康唑敏感率较低,但仍然有效。Objective To understanding the vaginal fungus infection and drug resistance in female.Methods The specimens of patients whose smear test under microscope were fungus-positive in white vaginal discharge routine,it were cultured,identification and drug susceptibility testing.Results The highest detection rate was Candida albicans（84 isolates,61.3%） in the 137 samples for inspection.Followed was Candida glabrata（19 isolates,13.9%）,Candida tropicalis（15 isolates,10.9%）,Candida krusei（7 isolates,5.1%）,and others fungi（12 isolates,8.8%）.The isolation-strain sensitivity rate in flucytosine,amphotericin B and voriconazole were all more than 90%.The rate in itraconazole and fluconazole were 84.7% and 70.8%.Conclusion The main source of infection is Candida albicans in female vaginal fungal infection.The isolationstrain sensitivity rate in flucytosine,amphotericin B and voriconazole are high.The rate in itraconazole and fluconazole are lower,but still valid.

关 键 词：真菌感染 假丝酵母菌 抗真菌药 敏感率 

分 类 号：R446.5[医药卫生—诊断学]