HBV感染标志物检测的临床价值比较  

The correlation and clinical significance of HBV infection makers

作　　者：邱家洋[1] 李良军[1] 杨帆[1] 

机构地区：[1]淮南市第一人民医院检验科,安徽省淮南232007

出　　处：《中国基层医药》2011年第7期879-880,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨HBV几种感染标志物的内在联系及临床意义。方法对106例样本分组检测HBV Pre SI-Ag、HBV—M（HBsAg、HBsAb、HBeAg、HBeAb、HBcAb）和HBV DNA并进行统计分析。结果106例样本中HBVPre SI-Ag和HBV DNA的总检出分别是86例（81．1％）和90例（84．9％）。在41例HBeAg阳性者中，Pre SI-Ag和HBV DNA的检出率分别为39例（95．1％）和37例（90．2％），而HBeAg阴性组65例中Pre SI-Ag和HBVDNA检出率分别为47例（72．3％）和53例（81．5％）。结论Pre SI-Ag和HBV DNA是诊断和判断HBV复制有价值的指标，常规筛查中Pre SI-Ag、HBV DNA监测优于HBeAg。Objective To explore the internal relations of HBV markers and its clinical significance. Methods HBV Pre SI-Ag.HBV-M（HBsAg,HBsAb.HBeAg,HBeAb.HBcAb） and HBV DNA of 106 patients were detected by ELISA and FQ-PCR respectively. Results The total positive rates of Pre-SI antigen and HBV DNA in 106 cases were 81.1% and 84.9% respectively. In 41 HBeAg-positive eases, Pre SI-Ag and HBV DNA detection rate was 95. 1% ,90. 2%. And HBeAg-negative 2 groups Pre SI-Ag and HBV DNA detection rate was also higher. Conclusion HBV Per SI-Ag was a very valuable serum marker in terms of direct HBV replication alone can not HBeAg-positive to determine whether the replication of the virus.

关 键 词：生物学标记 DNA病毒感染 

分 类 号：R51[医药卫生—内科学] R44[医药卫生—临床医学]