Effective gene silencing in Drosophila ovarian germline by artificial microRNAs  

作　　者：Hailong Wang YanJun Mu Dahua Chen 

机构地区：[1]State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Datun Road, Chaoyang, Beijing 100101, China

出　　处：《Cell Research》2011年第4期700-703,共4页细胞研究(英文版)

摘　　要：Dear Editor, Drosophila oogenesis is of great interest because it represents an excellent model system to study a number of fascinating biological processes, such as stem cell regulation, germ cell meiosis and oocyte determination, as well as signal interactions between germline and soma. A typical Drosophila ovary is composed of 16-20 ovarioles, each consisting of an anterior functional unit called a germarium and a linear string of differentiated egg chambers posterior to the germarium [1] (Figure 1A and 1B).

关 键 词：生殖细胞 小分子RNA 卵巢管 基因沉默 果蝇 人工 生物过程 模型系统 

分 类 号：Q949.718.2[生物学—植物学] Q52