自体造血干细胞移植造血功能重建后不明原因低热13例临床分析  

Low fever of unknown reason in patients undergoing autologous stem cell transplantation after hematopoietic reconstitution: a clinical analysis of 13 cases

作　　者：楼方定[1] 欧阳桂芳[2] 张伯龙[1] 王全顺[1] 王小沛[1] 姚善谦[1] 刘海川[1] 

机构地区：[1]解放军总医院血液科,北京100853 [2]宁波市第一医院血液科,进修医师315010

出　　处：《中华内科杂志》1999年第9期625-627,共3页Chinese Journal of Internal Medicine

摘　　要：目的　探讨自体造血干细胞移植患者在造血功能重建后低热原因。方法　对 13例自体造血干细胞移植患者在造血功能重建后低热原因作了综合分析研究。结果　通过症状、体征、实验室有关检查、影像学和病原学等综合分析 ,未找到任何发热原因 ,抗生素治疗无效 ,短期内应用小剂量泼尼松 5～ 10mg/d或氟美松 1～ 4mg/d ,使所有患者低热完全消退。结论　低热原因不明 ,可能系由大剂量放、化疗等综合因素引起的非特异性低热。Objective To investigate the reason of low fever in patients undergoing autologous stem cell transplantation after hematopoietic reconstitution. Methods The reasons for low fever in 13 patients undergoing autologous stem cell transplantation after hematopoietic reconstitution were comprehensively analyzed. Results After analysis of clinical features, laboratory tests, imaging and microbiological data, no reason was found for the low fever. There was no effect on the fever with anti microbial therapy. However the low fever was controlled by low dose prednisone 5～10 mg/d or dexamethasone 2～4 mg. Conclusion The reason for the low fever is not clear; it is probably nonspecific low fever induced by high dose radiotherapy or high dose chemotherapy.

关 键 词：造血干细胞移植 自体移植 发热 原因不明 

分 类 号：R457.7[医药卫生—治疗学]