女性脑梗死患者的血清E2水平与颈动脉斑块稳定性的关系  

作　　者：张伟丹[1] 王吉凤[1] 刘文帅[1] 

机构地区：[1]德州市人民医院急诊科,山东德州253014

出　　处：《中国中医药咨讯》2011年第12期307-308,共2页

摘　　要：目的：探讨女性脑梗死患者的血清E2与颈动脉斑块稳定性的关系。方法：将98例女性脑梗死患者按绝经与否分为绝经前组和绝经后组，测定患者血清中E2、hs—CRP水平，并用超声检测颈动脉内膜厚度及斑块。结果：绝经后组不稳定斑块为23．97％（29／121）明显高于绝经前组10．26％（4／39），两组比较有明显差异（P〈0．01）；绝经后组稳定斑块为76．03％（92／121）明显低于绝经前组89．74％（35／39），两组比较有明显差异（P〈O．01）。结论：血清E2与颈动脉斑块的稳定性有密切关系。Objective：To investigate the relationship of serum estradiol and the stability of carotid plaque To Women withcerebral infarction. Methods： Ninety-eight Women with cerebralinfarction were divided into remenopausal group and postmenopausal group according to whether post-menopausal. The levels of the serum estradiol and hs-CRP were detected. Carotid intima-media thickness and plaque were analyzed by carotid artery ultrasound. Results： Unstable plaques in postmenopausal group was 23.97% （29/121） was higher than pre-menopausal group 10.26% （4/39）, two groups were significantly different （P 〈0.01）;stable plaque postmenopausal group was 76.03% （92/121） was significantly lower than pre-menopausal group 89.74% （35/39）, the two groupsere significantly different （P〈0.01）. Conclusion： the close correlation was between Serum E2 and the stability of carotid plaque

关 键 词：脑梗死 女性 颈动脉斑块E2 hs—CRP 

分 类 号：R692.5[医药卫生—泌尿科学]