氯化消毒对自来水致突变性影响研究  

THE GENETIC TOXICOLOGIC EFFECT OF CHLORINATING DISINFECTION ON DRINKING WATER

作　　者：张淑琪[1] 王根凤[1] 王占生[1] 

机构地区：[1]清华大学环境科学与工程系,北京100084

出　　处：《癌变．畸变．突变》1999年第5期224-226,共3页Carcinogenesis,Teratogenesis & Mutagenesis

摘　　要：本文通过鼠伤寒沙门氏菌致突变试验（ Ａｍｅｓ Ｔｅｓｔ） ，分析常用氯化消毒方法对饮用水遗传毒性的影响。水样采自某单位自备水源。试验结果表明，未氯化自来水有机提取物致突变反应阴性，加氯自来水样诱发沙门氏菌致突变率升高；在一定范围内，随氯浓度增加，不会显著增加水样的致突变性。同时检测加氯后中和水样的致突变性，加中和剂处理后水样致突变性降低。提示加氯消毒水样致突变性可以通过水处理工艺加以改进，为饮水氯化消毒的致突变研究及其防治提供毒理学依据。By means of Ames test, the genetic toxicology of chlorination on drinking eater is evaluated. The result showed that the mutagenecity of water increased in all samples treated with chlorine, while mutagenic potential was negative in source water samples not treated with chorine. By adding Na\-2S\-2O\-3 to chlorinated water samples, there had less mutagenic activity. The antimutagenic potentials of Na\-2S\-2O\-3 in the chlorine water was dose dependent, the higher the mutagenicity of chlorined water, the better the beneficial effect of nasal. These indicated that the mutagenecity in chlorined water can be reduced by water treatment process.

关 键 词：致突变性 AMES试验 氯化 饮用水 

分 类 号：R123.1[医药卫生—环境卫生学]