细菌耐药性产生的原因、机制及防治措施  

The Causes,Mechanism and Preventive Measures of Bacterial Resistance

作　　者：赵明秋[1] 沈海燕[1] 潘文[1] 王佳莹[1] 李银光[1] 常艳[1] 

机构地区：[1]华南农业大学兽医学院,广东广州510642

出　　处：《中国畜牧兽医》2011年第5期177-181,共5页China Animal Husbandry & Veterinary Medicine

摘　　要：20世纪40年代青霉素的问世将人类带入了抗生素时代,抗感染治疗由此进入了新纪元,感染性疾病的病死率大大降低。半个世纪以来,人类一直把抗菌药物作为抗感染治疗最有力的武器。然而随着抗菌药物的广泛应用,感染性疾病的治疗又遇到了新的挑战——细菌对抗生素产生了耐药性,而此种耐药性表现为抗菌药物使用得越多耐药性亦变得越严重。目前已发现某些细菌对现有的几乎全部抗菌药物产生耐药,超级细菌的出现使人类有可能再次回到面临感染而无药可医的困境,控制细菌耐药性的增长已成为医学界乃至全人类的当务之急。正在逐渐建立自己的细菌耐药监测网络,监测细菌耐药的流行状况和规律,研究细菌产生耐药性的机制。With the advent of penicillin in the 1940s an era of antibiotics was started,anti-infection treatment thus entered a new era,the mortality rate of infectious diseases decreased dramatically.For a half century,humans have always considered antibacterial drugs as the most powerful weapon of anti-infection treatment.However,with the wide application of antimicrobial agents,the treatment of infectious diseases also meet the new challenges-bacterial resistance to antibiotics,which become more serious as the usage of antimicrobial is increased.Currently some bacteria have been found susceptible to almost all the antimicrobial agents,the appearance of super bacteria may bring humans back to the dilemma of no medicine for infectious diseases,so the control of the increase of bacterial resistance has become urgent for medicine and humankind.Our country is gradually building our own monitoring network of bacterial resistance,monitoring of the current epidemic status and trends of bacteria resistant,studying on the mechanism of bacteria resistant.

关 键 词：细菌 耐药性 防治 

分 类 号：S852.61[农业科学—基础兽医学]