本院220例药品不良反应报告及分析  

Report and Analysis of 220 Cases of Adverse Drug Reactions

作　　者：梁增杰[1] 邓增潮[1] 李林[1] 

机构地区：[1]高州市人民医院,广东高州525200

出　　处：《今日药学》2011年第4期248-250,共3页Pharmacy Today

摘　　要：目的了解本院药品不良反应（ADR）发生的特点,促进临床合理用药。方法对本院2008-01~2010-12收集到的220例ADR报告分别从患者的性别、年龄、给药途径、药品种类及临床表现等方面进行回顾性统计分析。结果 220例ADR的给药途径以静脉滴注为主（92.3%）,以抗感染药物引起的ADR居首位（44.1%）,其次是中药制剂（20.5%）;临床表现以皮肤及其附件损害最常见（46.8%）。结论应加强ADR监测,减少不良反应的发生,确保临床用药安全、有效、合理。Objective To investigate the features of adverse drug reactions（ADRs） in our hospital,so as to promote the rational drug usage of clinic.Methods A total of 220 ADRs cases were collected in our hospital from 2008-01~2010-12,then were analyzed retrospectively in respect of patients＇ sex and age,routes of administration,drug kinds and clinical manifestations etc.Results The main route of administration was by intravenous drip（92.3%） in the 220 ADRs,mainly anti-infective drugs（44.1%）,followed by traditional Chinese medicines（20.5%）.The ADRs were chiefly characterized by the lesions of skin and appendages（46.8%）.Conclusion ADRs monitoring should be strengthened to ensure the safe,effective,and rational drug usage in the clinic,and to decrease the reappearance of ADRs.

关 键 词：药品不良反应 监测 分析 合理用药 

分 类 号：R96[医药卫生—药理学]