国内外关于左炔诺孕酮紧急避孕药不良反应的数据分析与评价  

Analysis and Evaluation of Adverse Drug Reactions of Levonorgestrel Emergency Contraception at Home and Abroad

作　　者：朱向 李瑛[1,2] 

机构地区：[1]国家人口计生委计划生育药具不良反应监测中心 [2]江苏省计划生育科学技术研究所,南京市210036

出　　处：《中国药房》2011年第20期1835-1837,共3页China Pharmacy

基　　金：国家"十一五"科技支撑计划课题(2006BAI15B07)

摘　　要：目的:为我国左炔诺孕酮紧急避孕药安全使用与评价提供参考。方法:对美国食品与药品管理局医药产品不良事件报告体系、我国国家药品不良反应监测中心、世界卫生组织和我国国家人口计生委计划生育药具不良反应监测中心所收集到的左炔诺孕酮紧急避孕药不良反应报告进行分析,并对左炔诺孕酮紧急避孕药的不良反应进行文献检索与分析,找出国内、外关于左炔诺孕酮紧急避孕药不良反应发生类型与报告数据的差距并分析原因。结果:国内、外关于左炔诺孕酮紧急避孕药不良反应的发生类型、种类和报告数据方面均存在较大差距。结论:左炔诺孕酮紧急避孕药不良反应的公众教育、发放人员的专业培训及医师对紧急避孕药不良反应的认知与及时处理是减少与预防紧急避孕药不良反应发生的关键。OBJECTIVE： To provide reference for safe use and evaluation of levonorgestrel emergency contraception in China. METHODS： By the means of literature retrieval and analysis, the reports of adverse drug reactions induced by levonorgestrel emergency contraception from MedWatch （FDA Medical Products Reporting Program）, National Center for ADR Monitoring, WHO and State Contraceptives Adverse Reaction Surveillance Center were analyzed to find out the differences of types and data of adverse drug reactions induced levonorgestrel emergency contraception and analyze the reasons. RESULTS： There were large type and data differences of adverse drug reactions induced by levonorgestrel emergency contraception at home and aboard. CONCLUSION： The public education, professional training of issue personnel and the cognition of doctors and immediate processing are key to reduce and prevent the adverse drug reaction induced by emergency contraception.

关 键 词：左炔诺孕酮 紧急避孕 不良反应 

分 类 号：R711[医药卫生—妇产科学] R96[医药卫生—临床医学]