肺纤维化相关因子研究进展  

RESEARCH PROGRESS ON THE PULMONARY FIBROSIS-RELATED FACTORS

作　　者：徐慧蓉[1] 马小兵[1] 王献华[1] 

机构地区：[1]华北煤炭医学院病理学教研室,唐山063000

出　　处：《现代预防医学》2011年第10期1953-1955,1964,共4页Modern Preventive Medicine

基　　金：河北省自然科学基金资助项目(C2008001007);河北省科学技术研究与发展计划项目(09276192D)

摘　　要：肺纤维化是多种疾病共有的、不明原因的、以胶原在肺组织沉积为特征的一种病理过程,多种因子,诸如细胞因子、蛋白酶系统及转录因子在肺纤维化的发生、发展过程中起着重要的作用。本文对肺纤维化相关因子的研究进展作一综述,以期进一步揭示肺纤维化发病机制,并探索有效的防治措施。Pulmonary fibrosis（PF）is an unexplained pathological process characterized by the deposition of collagen in lung tissue shared by a lot of diseases.Various factors such as cytokines,protease systems and transcription factors may contribute to the occurrence and development of PF.This article reviewED the current research progress on the effect of the related factors in PF,in order to bring to light the pathogenesis and look for effective treatments for it.

关 键 词：肺纤维化 细胞因子 蛋白酶系统 转录因子 

分 类 号：R563[医药卫生—呼吸系统]