双组分信号传导系统与变异链球菌的致病相关特性  

Two-component signal transduction system and the virulence-related characteristics of Streptococcus mutans

作　　者：陈娇[1] 周智[1] 蒋丹[1] 

机构地区：[1]重庆医科大学附属口腔医院牙体牙髓病科,重庆400015

出　　处：《国际口腔医学杂志》2011年第3期297-300,共4页International Journal of Stomatology

基　　金：重庆市自然科学基金资助项目(CSTC2007BB5272);重庆市卫生局科研课题基金资助项目(2008-2-249);重庆市教委科研课题基金资助项目(KJ060317)

摘　　要：双组分信号传导系统(TCSTS)在变异链球菌感受态形成、生物膜形成、结构稳定、菌素产生、产酸耐酸特性等毒力因子表达方面起着重要的作用,为其在菌斑生物膜中的竞争和生存提供了诸多生态性优势。本文就变异链球菌TCSTS的组成、TCSTS对变异链球菌致病相关特性的影响、TCSTS的应用意义等作一综述。Two-component signal transduction system（TCSTS） plays an important role in the expression of virulence factors of Streptococcus mutans,such as the competence development,the formation of biofilm,the stability of structure,the production of bacteriocin,and the properties of acid production and resistance.It provides many ecological advantages to compete and survive in the dental plaque.This article is a review about the composition of TCSTS of Streptococcus mutans,the effect of TCSTS on the virulence-related characteristics of Streptococcus mutans,and the application significance of TCSTS.

关 键 词：变异链球菌 密度感应信号系统 双组分信号传导系统 

分 类 号：R378[医药卫生—病原生物学]