Cu^(2+)络合法测定枸橼酸钙含量  

Determination of calcium citrate by complexometry with Cu^(2+)

作　　者：闫明[1,2] 邹梅娟[2] 程刚[2] 

机构地区：[1]辽宁省人民医院,辽宁沈阳110016 [2]沈阳药科大学药学院,辽宁沈阳110016

出　　处：《中国医药导报》2011年第14期62-63,共2页China Medical Herald

摘　　要：目的:建立一种测定枸橼酸钙含量的方法。方法:利用枸橼酸盐与Cu2+的络合物具有紫外吸收的特点,采用紫外分光光度法测定枸橼酸钙含量,CuSO4溶液浓度为0.005 mol/L,检测波长240 nm。结果:枸橼酸钙在4.06~48.72μg/mL浓度范围内线性关系良好,平均回收率为99.6%,RSD为0.9%。结论:Cu2+络合法简单、快速、稳定、准确。Objective： To establish the determination of calcium citrate. Methods： The content of calcium citrate was measured by UV. The concentration of CuSO4 was 0.005 mol/L. The detection wavelength was 240 nm. Calcium citrate formed a complex compound by reacting with Cu^2＋ which had a specific absorption. Results： It was linear in the concentra tion range of 4.06-48.72 μg/mL. The recovery was 99.6%, with RSD of 0.9%. Conclusion： The method is simple, rapid, stable and accurate.

关 键 词：枸橼酸钙 硫酸铜 络合物 紫外分光光度法 

分 类 号：R927.2[医药卫生—药学]