血清蛋白电泳在病毒性肝炎中的应用和研究现状  

Application and research status of serum protein electrophoresis in virus hepatitis

作　　者：史慧慧[1] 张占卿[1] 

机构地区：[1]上海市（复旦大学附属）公共卫生临床中心肝炎二科,上海201508

出　　处：《世界感染杂志》2011年第2期84-86,136,共4页World Journal of Infection

基　　金：基金项目：上海市科委科技计划项目（09411965800）

摘　　要：在病毒性肝炎领域，血清蛋白电泳主要用于肝炎后肝硬化的辅助诊断。本文对血清蛋白电泳在病毒性肝炎诊断和病情评估中的研究现状进行综述。血清蛋白电泳对急性肝炎没有诊断价值，对慢性肝炎、重型肝炎和肝炎后肝硬化有诊断意义，对慢性肝炎的疾病程度有一定的判别价值。基于慢性肝炎血清蛋白电泳图谱构建新的数学模型可能提升血清蛋白电泳的应用价值。In the fields of viral hepatitis practice, serum protein electrophoresis is used in auxiliary diagnosis of hepatitis associated cirrhosis. In this paper, the research situation of serum protein electrophoresis for diagnosing viral hepatitis and evaluating the disease status of viral hepatitis were reviewed. Serum protein electrophoresis has no significance for diagnosing acute hepatitis, but has important significance for diagnosing chronic hepatitis, severe hepatitis and hepatitis associated cirrhosis. Serum protein electrophoresis has value for discriminating disease level of chronic hepatitis to some extent. The newer built mathematic models based on the spectrum of serum protein electrophoresis in chronic hepatitis could upgrade the application value of serum protein electrophoresis.

关 键 词：血清蛋白电泳 病毒性肝炎 急性肝炎 重型肝炎 肝炎后肝硬化 疾病程度 

分 类 号：R512.6[医药卫生—内科学] R446.112[医药卫生—临床医学]