糖尿病周围神经病变的中医证型分布规律研究  

Study on TCM Syndrome Distribution Law of Diabetic Peripheral Neuropathy

作　　者：王志强 庞国明 闫镛 姚沛雨 

机构地区：[1]开封市中医院糖尿病科,河南开封475001

出　　处：《中医学报》2011年第4期487-489,共3页Acta Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)资助项目(编号:2005CB523501);国家中医药管理局资助项目(编号:ZYYXH/T3.1-3.15-2007)

摘　　要：目的:探讨糖尿病周围神经病变中医证型分布规律,为糖尿病周围神经病变的中医辨证分型提供依据,进而为有效的指导临床论治,提升治疗效果。方法:通过对200例确诊为糖尿病周围神经病变的患者进行回顾性分析,根据《糖尿病中医防治指南》对该病的分型标准,按照统计学方法,探讨该病的证型分布规律。结果:本病证型分布由大到小依次为:气虚血瘀型>阴虚血瘀型>痰瘀阻络型>肝肾亏虚型,病机演变过程:随着糖尿病的发展糖尿病周围神经病变按照气(阴)虚血瘀→气阴两虚血瘀→阳虚血瘀→肝肾亏虚血瘀的规律而演变。结论:阴亏是发生DPN的关键;气虚是迁延不愈的症结;阳虚是发展的必然趋势;血瘀贯穿DPN的始终。Objective： To explore TCM syndrome type distribution law of peripheral neuropathy in diabetes, thus providing basis for clinical differentiation and treatment and promoting curative effects. Methods ：200 patients who were diagnosed as diabetic peripheral neurop- athy were retrospectively analyzed. According to the classification standards in the Guidelines of the TCM Prevention and Treatment of Diabetes and the statistical methods ,the syndrome distribution law was discussed. Results： Syndrome distribution is as follows： qi deficiency with blood stasis 〉 yin deficiency with blood stasis 〉 phlegm and stasis obstructing the meridians 〉 kidney and liver deficiency. The pathogenesis evolution is as follows, with the development of diabetes, diabetic peripheral neuropathy also developed in accordance with qi deficiency with blood stasis or yin deficiency with blood stasis to qi and blood deficiency with blood stasis,then yang deficiency with blood stasis, and at last to the kidney and liver deficiency. Conclusion：Yin deficiency is the key for the occurrence of DPN with qi - deficiency as the reason for protracted course of disease, yang - deficiency as the inevitable trend of development and blood stasis as the factor that penetrates throughout DPN.

关 键 词：糖尿病周围神经病变 中医证型 症状 

分 类 号：R259.871[医药卫生—中西医结合]