无痛内镜下十二指肠乳头括约肌切开术应用丙泊酚复合芬太尼的麻醉效果及安全性评价  

Clinical application of Propofol combined with Fentanyl in painless endoscopic sphincterotomy

作　　者：陈堃[1] 林丽[1] 王寿军[1] 

机构地区：[1]成都市第六人民医院麻醉科,四川成都610051

出　　处：《实用医院临床杂志》2011年第3期91-93,共3页Practical Journal of Clinical Medicine

摘　　要：目的探讨丙泊酚复合芬太尼用于无痛内镜下十二指肠乳头括约肌切开术(EST)的麻醉效果及其安全性。方法 60例拟行EST的患者被分为A、B两组各30例,A组采用无痛EST,B组行常规EST。观察比较两组患者手术期间的生命体征的变化,不良反应以及术后感受,并记录两组手术操作时间、手术成功率。结果 A组术中平均动脉压(MAP)、心率(HR)及血氧饱和度(SpO2)呈一过性下降,B组术中HR及MAP升高,与术前及A组术中相比差异有统计学意义(P<0.05);A组手术成功率高,不良反应低,患者满意率高;两组操作时间比较,差异无统计学意义(P>0.05)。结论丙泊酚复合芬太尼用于无痛EST安全舒适有效、清醒快、不良反应少、患者更满意,值得临床推广应用。Objective To discuss the efficacy and safety of Propofol combined with Fentanyl for anesthesia of endoscopic sphincterotomy（EST）.Methods Sixty patients scheduled for EST were assigned to either group A（n=30） or group B（n=30）.Group A was intravenously given Propofol combined with Fentanyl.Group B was intravenously given Sodium Chloride.Changes of vital signs such as MAP,HR and SPO2,incidence of adverse reactions and postoperative feeling were observed.Operation time and success rate were recorded.Results Transient decreases were observed in HR,MAP and SpO2 in group A.HR and MAP increased during operation,which was significantly different than those before operation and those in group B（P 0.05）.Compared with group B,group A showed higher success rate,less adverse reactions and higher satisfaction of patients.There was not significant difference in operation time between the two groups（P 0.05）.Conclusion The therapy of Propofol combined with Fentanyl for EST,which is safe,comfortable and effective,is suggested to be applied in clinic for its short recovery time,less adverse reactions and higher satisfaction of patients.

关 键 词：丙泊酚 芬太尼 内镜下十二指肠乳头括约肌切开术 无痛 内镜 

分 类 号：R614[医药卫生—麻醉学] R656[医药卫生—外科学]