卡介苗素联合左旋咪唑治疗小儿反复呼吸道感染的疗效研究  

Study on Effect of Bacillus Calmette-Guerin Combined with Levamisole in Treating Children with Recurrent Respiratory Tract Infections

作　　者：陈晓玲[1] 王宇[1] 王玉玲[1] 

机构地区：[1]广东省佛山市南海区盐步医院,广东佛山528247

出　　处：《临床医学工程》2011年第5期697-698,共2页Clinical Medicine & Engineering

摘　　要：目的探讨卡介苗素联合左旋咪唑治疗小儿反复呼吸道感染(RRTI)的临床效果。方法将2008年1月～2009年1月间在我院住院治疗的RRTI患儿随机分为治疗组和对照组,两组均给予常规治疗,治疗组同时给予卡介苗素联合左旋咪唑治疗。结果治疗组CD3+、CD4+以及CD4+/CD8+明显高于对照组,两组比较差异具有统计学意义(P<0.05);治疗组在呼吸道感染次数、发热时间、咳嗽时间、抗生素使用时间方面明显优于对照组,两者分别比较差异具有统计学意义(P<0.05);治疗组总有效率为95.00%,对照组为65.00%,两者比较差异具有统计学意义(P<0.05);两组患儿均未见明显的治疗不良反应。结论卡介苗素联合左旋咪唑治疗小儿反复呼吸道感染的临床效果确切,无毒副作用,值得推荐应用。Objective To investigate the effect of bacillus calmette-guerin combined with levamisole in treating children with recurrent respiratory tract infections.Methods The children with RRTI in our hospital from January in 2007 to January in 2008 were divided into the treatment group and the control group.The both of groups received the conventional therapy,and the treatment group received the treatment of bacillus calmette-guerin combined with levamisole.Results The levels of CD3＋,CD4＋ and CD4＋/CD8＋ in treatment group were higher than those in control group,and there was significant difference in them（P〈0.05）.The times of fever,cough,using the antibiotics and frequency of respiratory infection in the treatment group were superior to those in the control group,with significant difference（P〈0.05）.The total effective rate was 95.00% in the treatment group and 65.00% in the control group,with significant difference（P〈0.05）.There was no significant untoward reaction in all of the children.Conclusion The effect of bacillus calmette-guerin combined with levamisole in treating children with recurrent respiratory tract infectionsis is obvious with no side effect,which is worthy of wide application.

关 键 词：卡介苗素 左旋咪唑 小儿 反复呼吸道感染 

分 类 号：R725.6[医药卫生—儿科]