多巴胺与去甲肾上腺素在感染性休克中的应用进展  

Research Progress in Dopamine and Norepinephrine for the Treatment of Septic Shock

作　　者：刘畅[1] 胡志[1] 金晓东[1] 康焰[1] 

机构地区：[1]四川大学华西医院重症监护室,成都610041

出　　处：《医学综述》2011年第9期1361-1363,共3页Medical Recapitulate

摘　　要：感染性休克是一种复杂、高病死率的临床综合征,是重症监护病房最常见的死亡原因之一,严重威胁着人类的健康。多巴胺和去甲肾上腺素对肾脏及其他内脏均产生重要的影响,可作为一线升压药物,但多巴胺较去甲肾上腺素加快心率的作用更明显。在治疗感染性休克过程中,应早期诊断及识别一些死亡危险因素,也需要更多的循证医学证据,以期及时给予有力的干预措施,进一步提高感染性休克的救治成功率,这是降低病死率的关键。Septic shock is a complex clinical syndrome with a high mortality,as one the of most frequent causes of intensive care unit deaths that seriously threaten human health.Dopamine and norepinephrine can be used as the first-line hypertensive agents due to their remarkable effects on kidney and other organs,whereas dopamine has a more significant tachycardiac effect than norepinephrine.In the treatment of septic shock,early diagnosis and identification of mortality-associated risk factors are required,including more evidence-based medicine involvement.Appropriate and potent management in attempt to maximize the rescue rate of septic shock is critical for the minimization of mortality.

关 键 词：感染性休克 多巴胺 去甲肾上腺素 

分 类 号：R631[医药卫生—外科学]