运动引起的白细胞介素6的改变与铁调素的调控  

The Regulatory Mechanism of Hepcidin Expression by Interleukin 6(IL-6) in Exercise

作　　者：闫芬[1] 李颖[1] 刘树欣[1] 刘玉倩[1] 

机构地区：[1]河北师范大学体育学院,河北石家庄050024

出　　处：《河北师范大学学报（自然科学版）》2011年第3期305-308,324,共5页Journal of Hebei Normal University：Natural Science

基　　金：国家自然科学基金(30700390);河北省自然科学基金(C2009000291)

摘　　要：运动可改变机体铁状态,过度运动会引起机体铁缺乏,甚至导致机体出现运动性贫血,影响运动员成绩.近几年研究表明铁调素(Hepcidin)是调控机体铁代谢的关键因素,而运动中产生的白细胞介素6(IL-6)是影响Hepcidin表达变化的重要原因之一.介绍了IL-6对Hepcidin表达的影响、运动对IL-6表达调控的研究进展,综合分析了运动引起的IL-6的改变及其对Hepcidin的调控机制.The iron status can be changed during exercise.Excessive exercise can lead to iron deficiency,even sports anemia.Accordingly athletes performance is greatly affected by iron status.The researches on the regulatory mechanism of iron metabolism show that hepcidin plays an important role in iron metabolism,and IL -6 is one of the important reasons for the expression of hepcidin in exercise.This review reveals the regulaory mechanism of IL-6 on hepcidin expression in exercise.

关 键 词：运动 白细胞介素6 铁调素 

分 类 号：G804.7[文化科学—运动人体科学]