弱碱性阴离子交换树脂去除青霉素中的杂质  

The Impurity in Penicillin Removed by Weak Alkali Anions Resin

作　　者：刘建辉[1] 赵素霞[1] 李晓梅[1] 郭军臣 纪爱民[1] 王兴[1] 

机构地区：[1]石药集团河北中润制药有限公司,河北石家庄050041

出　　处：《河北化工》2011年第5期25-28,共4页Hebei Chemical Industry

摘　　要：探索了用弱碱性阴离子交换树脂去除青霉素中的聚合物杂质。通过对树脂性能进行研究分析,将离子交换树脂应用于青霉素生产中,筛选出具有青霉素杂质去除能力的XX-16弱碱性阴离子树脂,通过树脂的选择性交换和吸附,将青霉素中的杂质进行有效吸附,有效降低了青霉素中的聚合物含量。To explore how the polymer in penicillin was removed by weak alkali ion exchange resin.The ion exchange resin was applied to penicillin production and XX-16 weak-base anion-exchange resin which can remove the impurities in penicillin was selected.The impurities were effectively absorbed by selective exchange and adsorption of resin.Therefore,the polymer in penicillin can be effectively removed.

关 键 词：杂质 离子交换树脂 青霉素 

分 类 号：TQ465.1[化学工程—制药化工]