广西沿海平颏海蛇和青环海蛇化学成分分析  

CHEMICAL ANALYSIS OF LAPEMIS HARDWICKII AND HYDROPHIS CYANOCINCTUS FROM GUANGXI

作　　者：周琦[1] 王雪芬[1] 陈家源[1] 卢文杰[1] 

机构地区：[1]广西中医药研究所,530022

出　　处：《中国海洋药物》1999年第3期19-22,共4页Chinese Journal of Marine Drugs

摘　　要：通过建立小鼠急性肝损伤及大鼠慢性肝损伤模型，观察并研究海洋药物Ｊ－ ９１１对小鼠急性肝损伤及大鼠慢性肝损伤的保护作用。结果表明，Ｊ－９１１能明显降低Ｄ－半乳糖胺引起急性肝损伤小鼠的血清ＡＬＴ升高和四氯化碳引起的急性肝损伤小鼠的血清ＡＬＴ、ＡＳＴ的升高，明显减轻模型肝组织病理损伤。Ｊ－９１１还可显著降低肝纤维化大鼠血清ＡＬＴ、ＡＳＴ水平及肝组织羟脯氨酸含量，并明显减轻肝组织病理损伤。说明Ｊ－９１１对实验性肝损伤具有保护作用。Lapemis hardwickii and Hydrophis cyanocinctus from Guangxi were analysed by Kjeldahl method, auto-analysis of amino acids, gas chromatography, atomic absorption spectrometry and other meth ods. The results showed that their contents of total nitrogens, proteins, amino acids, fatty acids, trace ele ments were approximation. It will provide scientific evidence for development of the medicinal resources and the establishment of quality standards.

关 键 词：海蛇科 平颏海蛇 青环海蛇 化学分析 

分 类 号：R931.74[医药卫生—生药学]